Casidone

Casidone Uses, Dosage, Side Effects, Food Interaction and all others data.

Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.

Providone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone that is used as a binder in many pharmaceutical tablets and lubricant in eye drops. It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. When in complex with iodine, Povidone-iodine displays antiseptic properties where the iodine, a bactericidal component, mainly contributes to this effect and povidone acts as a carrier . Povidone-iodine can be found in over-the-counter topical solutions, ointment, pessaries, liquid soaps and surgical scrubs. The clinical effectiveness of Povidone-iodine on wound healing remains somewhat controversial, as it was demonstrated in few clinical studies that application of the compound in wounds was associated with impaired wound healing, reduced wound strength, or infection in open wounds .

Povidone itself has no microbicidal activity. Povidone-iodine exhibits rapid, potent, broad-spectrum antimicrobial properties . The clinical effectiveness of povidon-iodine on wound healing remains somewhat controversial; in few clinical studies investigating the effects of povidone-iodine on wound healing, topical administration of the complex was associated with no significant infections, but slower healing and mild to moderate discomfort on application .

Trade Name Casidone
Generic Povidone + Iodine
Type Solution
Therapeutic Class
Manufacturer
Available Country India
Last Updated: September 19, 2023 at 7:00 am
Casidone
Casidone

Uses

Iodine is an ingredient of nutritional supplements that is also used for disinfection.

Investigated for use/treatment in breast disorders (unspecified) and pain (acute or chronic).

When in complex with iodine, indicated for inducing antisepsis for prevention of infection in minor cuts, scrapes, and burns.

Casidone is also used to associated treatment for these conditions: Infection in minor cuts, scrapes, or burns, Antisepsis, Antimycotic, Prophylaxis of bacterial skin infectionsDry Eyes, Skin disinfection

How Casidone works

Molecular iodine is known to inhibit the induction and promotion of N-methyl-n-nitrosourea-induced mammary carcinogenesis, to regress 7,12-dimethylbenz(a)anthracene-induced breast tumors in rats.It has also been shown to have beneficial effects in fibrocystic human breast disease.

Povidone-iodine is a water-soluble complex that mediates a bactericidal or virucidal action following the gradual liberation of free iodine from the complex at the application site to react with the pathogen . Please refer to the drug entry for Povidone-iodine for the full mechanism of action of the complex.

Toxicity

Oral LD50 in mouse, rat, and rabbit are >40 mg/kg, 100 mg/kg, and 1040 mg/kg, respectively . No cases of overdose in humans have been reported.

Volume of Distribution

This pharmacokinetic data does not apply to povidone.

Elimination Route

This pharmacokinetic data does not apply to povidone.

Half Life

This pharmacokinetic data does not apply to povidone.

Clearance

This pharmacokinetic data does not apply to povidone.

Elimination Route

This pharmacokinetic data does not apply to povidone.

Innovators Monograph

You find simplified version here Casidone


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