Cefmenoxime
Cefmenoxime Uses, Dosage, Side Effects, Food Interaction and all others data.
Cefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically used in the treatment of female gynecologic and obstetric infections. It is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria.
Cefmenoxime is a semisynthetic beta-lactam cephalosporin antibiotic with activity similar to that of cefotaxime. It has broad spectrum activity against Gram positive and Gram negative bacteria.
Trade Name | Cefmenoxime |
Generic | Cefmenoxime |
Cefmenoxime Other Names | Cefmenoxima, Cefmenoxime, Cefmenoximum |
Type | |
Formula | C16H17N9O5S3 |
Weight | Average: 511.558 Monoisotopic: 511.051476769 |
Protein binding | 50-70% |
Groups | Approved |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Used to treat female gynecologic and obstetric infections caused by susceptible aerobic (including the gonococcus) and anaerobic bacteria.
How Cefmenoxime works
The bactericidal activity of cefmenoxime results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). Cefmenoxime is stable in the presence of a variety of b-lactamases, including penicillinases and some cephalosporinases.
Toxicity
Information on cefmenoxime overdosage in humans is not available. However, with other b-lactam antibiotics, adverse effects following overdosage have included nausea, vomiting, epigastric distress, diarrhea, and convulsions.
Elimination Route
Bioavailability is approximately 100% following intramuscular injection.
Half Life
1 hour
Innovators Monograph
You find simplified version here Cefmenoxime