Cefonicido Uses, Dosage, Side Effects and more

A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.

Cefonicido is a second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.

Trade Name	Cefonicido
Availability	Discontinued
Generic	Cefonicid
Cefonicid Other Names	Cefonicid, Cefonicido, Cefonicidum
Related Drugs	amoxicillin, doxycycline, ciprofloxacin, cephalexin, metronidazole, azithromycin, clindamycin, ceftriaxone, levofloxacin, Augmentin
Type
Formula	C₁₈H₁₈N₆O₈S₃
Weight	Average: 542.566 Monoisotopic: 542.034823652
Protein binding	98% bound to plasma proteins.
Groups	Approved, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	January 7, 2025 at 1:49 am

Uses

For the treatment of bacterial infections caused by susceptible microorganisms.

How Cefonicido works

Cefonicido, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins.

Cefonicido Hypertension interaction

[Moderate] Parenteral cefonicid sodium contains approximately 85 mg (3.7 mEq) of sodium per each gram of cefonicid activity.

The sodium content should be considered in patients with conditions that may require sodium restriction, such as congestive heart failure, hypertension, and fluid retention.