Cefroxadine

Cefroxadine Uses, Dosage, Side Effects, Food Interaction and all others data.

Cefroxadine is an orally available cephalosporin antibiotic. As part of its drug class, it shares structural properties to cefalexin as well as its activity spectrum. It was used in Italy but has since been withdrawn.

Cefroxadine is a cephalosporin antibiotic which produces a bactericidal effect on susceptible bacteria .

Cefroxadine
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Cefroxadine
Generic	Cefroxadine
Cefroxadine Other Names	Cefroxadine, cefroxadino
Type
Formula	C₁₆H₁₉N₃O₅S
Weight	Average: 365.4 Monoisotopic: 365.104541898
Protein binding	Cefrixadine is 10% bound to human plasma proteins .
Groups	Withdrawn
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Was used for the treatment of bacterial infections.

How Cefroxadine works

Cefrixadine is a cephalosporin antibiotic, a class of β-lactam antibiotics similar to penicillins, which binds to and inhibits penicillin binding proteins (PBPs) . PBPs are responsible for catalyzing the transpeptidase reaction which cross-links the peptide side chains on the sugar residues of a peptidoglycan unit, adding the unit to the peptidoglycan layer. This disrupts the balance between the hydrolysis of peptidoglycan, in order to insert new peptidoglycan units, by murein hydrolase and the attachment of the new units which leads to overall destruction of the peptidoglycan layer. With the loss of its peptidoglycan layer the cell also loses its resistance to the high osmotic pressure inside its membrane and lyses.