Ceftaroline Fosamil

Ceftaroline Fosamil Uses, Dosage, Side Effects, Food Interaction and all others data.

Ceftaroline Fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria:Acute bacterial skin and skin structure infections.Community-acquired bacterial pneumonia.

The time that unbound plasma concentration of ceftaroline exceeds the minimum inhibitory concentration (MIC) of the infecting organism has been shown to best correlate with efficacy in a neutropenic murine thigh infection model with S. aureus and S. pneumoniae.

No significant effect on QTc (corrected QT interval) interval was detected at peak plasma concentration or at any other time.

Table Of contents

• Ceftaroline Fosamil
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Ceftaroline Fosamil
Generic	Ceftaroline fosamil
Ceftaroline fosamil Other Names	Ceftarolina fosamilo, Ceftaroline, Ceftaroline fosamil, Ceftarolinum fosamilum
Type
Formula	C22H21N8O8PS4
Weight	Average: 684.67 Monoisotopic: 684.010281362
Protein binding	approximately 20%.
Groups	Approved, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Ceftaroline Fosamil is an antibacterial agent used to treat various bacterial infections, such as acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia.

Ceftaroline Fosamil is indicated for the treatment of patients with the following infections caused by susceptible isolates of the designated microorganisms.

Ceftaroline Fosamil is also used to associated treatment for these conditions: Bacterial Infections, Community Acquired Pneumonia (CAP), Acute skin and subcutaneous tissue bacterial infections

How Ceftaroline Fosamil works

Ceftaroline Fosamil is an antibacterial drug.

Toxicity

LD50/LC50: Draize test, rabbit, eye: 100 mg/24H Moderate; Oral, mouse: LD50 = 300 mg/kg; Oral, rabbit: LD50 = 3200 mg/kg; Oral, rat: LD50 = 980 mg/kg.

Food Interaction

No interactions found.

Volume of Distribution

Median 20.3 L (18.3-21.6 L).

Half Life

1.60 hours (600 mg dose).

Elimination Route

primarily eliminated by the kidneys (6% in feces within 48 hours).

Innovators Monograph

You find simplified version here Ceftaroline Fosamil