Ceftilox Cv Kid
Ceftilox Cv Kid Uses, Dosage, Side Effects, Food Interaction and all others data.
Ceftilox Cv Kid is a semi-synthetic, broad spectrum cephalosporin antibiotic of third generation for oral administration. It is a bactericidal antibiotic, kills bacteria by interfering in the synthesis of the bacterial cell wall. Ceftilox Cv Kid is highly stable in the presence of beta-lactamase enzymes. Ceftilox Cv Kid has marked in -vitro bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms including beta lactamase producers.
Clinical efficacy of Ceftilox Cv Kid has been demonstrated in infections caused by commonly occurring pathogens including Gram-positive organism Streptococcus pneumoniae, Streptococcus pyogenes, Gram-negative organism Escherichia coli, Proteus mirabilis, Klebsiella spp., Haemophilus influenzae (beta-lactamase positive and negative), Moraxella catarrhalis (beta-lactamase positive and negative), Salmonella typhi and Enterobacter species.
Ceftilox Cv Kid, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Ceftilox Cv Kid is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall.
| Trade Name | Ceftilox Cv Kid |
| Availability | Prescription only |
| Generic | Cefixime |
| Cefixime Other Names | Cefixim, Cefixima, Céfixime, Cefixime, Cefiximum |
| Related Drugs | amoxicillin, prednisone, doxycycline, ciprofloxacin, cephalexin, metronidazole, azithromycin, clindamycin, ceftriaxone, levofloxacin |
| Type | Tablet |
| Formula | C16H15N5O7S2 |
| Weight | Average: 453.45 Monoisotopic: 453.041289239 |
| Protein binding | 65% (concentration independent) |
| Groups | Approved, Investigational |
| Therapeutic Class | Third generation Cephalosporins |
| Manufacturer | Intra Life Pvt Ltd |
| Available Country | India |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Ceftilox Cv Kid is used for the following infectious diseases -
Respiratory Tract Infections:
Pneumonia
Sinusitis
Pharyngitis and Tonsillitis
Acute Bronchitis and Acute Exacerbations of Chronic
Bronchitis (AECB)
Otitis Media
Typhoid Fever
Urinary Tract Infections
Uncomplicated gonorrhea (cervical/urethral)
Ceftilox Cv Kid is also used to associated treatment for these conditions: Acute Exacerbation of Chronic Bronchitis caused by Streptococcus Pneumoniae, Acute Exacerbations of Chronic Bronchitis caused by Haemophilus Influenzae, Bacterial Sinusitis, Community Acquired Pneumonia (CAP), Gonorrhea of anus, Lyme Disease, Salmonella Infections, Salmonella Typhi Infection, Shigella Infection, Streptococcal Pharyngitis, Streptococcal tonsillitis, Uncomplicated Urinary Tract Infections, Bacterial otitis media, Bacterial rhinosinusitis, Uncomplicated Gonorrhea
How Ceftilox Cv Kid works
Like all beta-lactam antibiotics, cefixime binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefixime interferes with an autolysin inhibitor.
Dosage
Ceftilox Cv Kid dosage
The usual treatment of Ceftilox Cv Kid is 7 days. This may be continued for up to 14 days according to the severity of infection.
Ceftilox Cv Kid Capsule
Adult and child over 12 years: 200 or 400 mg daily as a single dose or in two divided doses.
Ceftilox Cv Kid Suspension
Child over 6 months: 8 mg/kg daily as a single dose or in 2 divided doses
Direction for Reconstitution of Suspension
• To prepare 50 ml suspension, 25 ml boiled and cooled water is required.
• To prepare 40 ml suspension, 20 ml boiled and cooled water is required.
• To prepare 30 ml suspension, 15 ml boiled and cooled water is required.
• To prepare 50 ml DS suspension, 25 ml boiled and cooled water is required.
Tap the bottle several times to loosen powder contents prior to reconstitution. Add approximately half of the total amount of water and shake well. Add remainder of water, and then shake again.
Note: Shake the suspension well before each use. Keep the bottle tightly closed. The reconstituted suspension should be stored in a cool and dry place, preferably in refrigerator and unused portion should be discarded after 14 days.
Side Effects
Ceftilox Cv Kid is generally well tolerated. The majority of adverse reactions observed in clinical trials are mild and self limiting in nature.
Gastro-intestinal disturbance: Diarrhea (if severe diarrhea occurs, Ceftilox Cv Kid should be discontinued), changes in the color of stool, nausea, abdominal pain, dyspepsia, vomiting, flatulence have been reported. CNS disturbances: Headache, dizziness.
Others: Hypersensitivity reactions which usually subsided upon discontinuation of therapy; infrequent and reversible hematological changes; elevation of serum amylase.
Toxicity
Symptoms of overdose include blood in the urine, diarrhea, nausea, upper abdominal pain, and vomiting.
Precaution
Ceftilox Cv Kid should be prescribed with caution in individuals with a history of gastrointestinal diseases, particularly colitis. Dosage adjustment is only necessary in severe renal failure (creatinine clearance < 20 ml/min)
Interaction
Increased prothrombin time (with or withot bleeding) with anticoagulants (e.g. warfarin). Increased plasma carbamazepine concentrations with concomitant use. Increased bioavailability with nifedipine. Increased serum concentration with probenecid.
Food Interaction
- Take with or without food.
Ceftilox Cv Kid Drug Interaction
Unknown: aspirin, aspirin, amoxicillin / clavulanate, amoxicillin / clavulanate, ciprofloxacin, ciprofloxacin, ginkgo, ginkgo, acetaminophen, acetaminophen, thiamine, thiamine, cyanocobalamin, cyanocobalamin, pyridoxine, pyridoxine, ascorbic acid, ascorbic acid, cholecalciferol, cholecalciferol
Ceftilox Cv Kid Disease Interaction
Major: colitisModerate: renal dysfunction, nitroprusside tests, liver disease, seizure disorders
Elimination Route
About 40%-50% absorbed orally whether administered with or without food, however, time to maximal absorption is increased approximately 0.8 hours when administered with food.
Half Life
3-4 hours (may range up to 9 hours). In severe renal impairment (5 to 20 mL/min creatinine clearance), the half-life increased to an average of 11.5 hours.
Pregnancy & Breastfeeding use
Pregnancy: Pregnancy category B. There are no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.
Lactation: It is not known whether Ceftilox Cv Kid is excreted in human milk. Consideration should be given to discontinuing nursing temporarily during treatment with this drug.
Use in Elderly
No special precautions are necessary. No dosage adjustment is required for elderly
Contraindication
Patients with known hypersensitivity to cephalosporin antibiotics, children under 6 months.
Special Warning
Use in Children: Safety and effectiveness of cefixime in children aged less than 6 months have not been established. For children younger than 12 years or weighing less than 50 kg, the usual dose is 8 mg/kg/day.
Use in elderly: No special precautions are necessary. Old age is not an indication for dose adjustment.
Dosage in renal impairment:
- Creatinine clearance: 20 ml/min or greater: normal dose
- Creatinine clearance: <20 ml/min or chronic ambulatory peritoneal dialysis
- Haemodialysis: daily dose should not exceed 200 mg.
Acute Overdose
Gastric lavage may be indicated; otherwise, no specific antidote exists. Ceftilox Cv Kid is not removed in significant quantities from the circulation by hemodialysis or peritoneal dialysis. Adverse reactions in small numbers of healthy adult volunteers receiving single doses up to 2 g of Ceftilox Cv Kid did not differ from the profile seen in patients treated at the recommended doses.
Interaction with other Medicine
Carbamazepine: Elevated carbamazepine levels have been reported in postmarketing experience when Ceftilox Cv Kid is administered concomitantly. Drug monitoring may be of assistance in detecting alterations in carbamazepine plasma concentrations.
Warfarin and Anticoagulants: Increased prothrombin time, with or without clinical bleeding, has been reported when cefixime is administered concomitantly.
Storage Condition
Store in a cool and dry place below 30ºC
Innovators Monograph
You find simplified version here Ceftilox Cv Kid
Ceftilox Cv Kid contains Cefixime see full prescribing information from innovator Ceftilox Cv Kid Monograph, Ceftilox Cv Kid MSDS, Ceftilox Cv Kid FDA label
FAQ
What is Ceftilox Cv Kid used to treat?
Ceftilox Cv Kid is used to treat bacterial infections in many different parts of the body.
How does Ceftilox Cv Kid work?
Ceftilox Cv Kid works by killing bacteria.
What are the common side effects of Ceftilox Cv Kid?
Common side effects of Ceftilox Cv Kid are include:
- diarrhea.
- stomach pain.
- gas.
- heartburn.
- nausea.
- vomiting.
Is Ceftilox Cv Kid safe during pregnancy?
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women. Use is recommended only if clearly needed and the benefit outweighs the risk.
Is Ceftilox Cv Kid safe during breastfeeding?
Ceftilox Cv Kid is acceptable in nursing mothers.
Can I drink alcohol with Ceftilox Cv Kid?
It Is generally OK to drink alcohol in moderation while taking Ceftilox Cv Kid.
Can I drive after taking Ceftilox Cv Kid?
If you experience any of these, do not drive any vehicle or use machinery.
How long does it take Ceftilox Cv Kid to work?
Ceftilox Cv Kid takes approximately 7 to 14 days to be effective and cure gonorrhoea. For other conditions, it may vary from individual to individual and their tolerance for the medicine. It's typically taken once or twice a day.
When should be taken of Ceftilox Cv Kid?
It is usually taken with or without food every 12 or 24 hours.
How long does Ceftilox Cv Kid stay in my system?
The half-life is about 3 to 4 hours and is not dose dependent.Ceftilox Cv Kid is excreted by renal and biliary mechanisms. About 50% of the absorbed dose is excreted unchanged in the urine within 24 hours.
How long does it take for Ceftilox Cv Kid to get out of your system?
Each antibiotic may stay in the body for different lengths of time, but common antibiotics such Ceftilox Cv Kid stay in your system for about 24 hours after taking the last dose. It might take longer for people with impaired kidney function to eliminate the drug from the body.
Can I take Ceftilox Cv Kid for a long time?
Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.
What happens if you stop taking Ceftilox Cv Kid?
If you stop taking Ceftilox Cv Kid too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.
Is Ceftilox Cv Kid safe for kidneys?
When acute renal failure occurs, Ceftilox Cv Kid should be discontinued and appropriate therapy and measures should be taken.
Who should not take Ceftilox Cv Kid?
You should not take Ceftilox Cv Kid if you are allergic to Ceftilox Cv Kid, or to similar antibiotics.Tell your doctor if you are allergic to Ceftilox Cv Kid.
How should I take Ceftilox Cv Kid?
You may take Ceftilox Cv Kid with or without food.The Ceftilox Cv Kid chewable tablet must be chewed before you swallow it.Follow all directions on your prescription label. Do not take Ceftilox Cv Kid in larger or smaller amounts or for longer than recommended.
What happens if I miss a dose of Ceftilox Cv Kid?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Can I take overdose on Ceftilox Cv Kid?
If Ceftilox Cv Kid is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.
How quickly does Ceftilox Cv Kid work?
Ceftilox Cv Kid takes approximately 7 to 14 days to be effective and cure gonorrhoea.
How much Ceftilox Cv Kid should I take to cure gonorrhea?
In the treatment of uncomplicated gonorrhea, a single dose of Ceftilox Cv Kid given orally appears to be as effective .
Is Ceftilox Cv Kid good for kidney?
About 20% of the Ceftilox Cv Kid is excreted by the kidneys as active drug.
Can Ceftilox Cv Kid damage liver?
Moderate Potential Hazard, Moderate plausibility. Cases of hepatitis have been reported with the use of certain cephalosporins.
