Cephalotin

Cephalotin Uses, Dosage, Side Effects, Food Interaction and all others data.

Cephalotin is a cephalosporin antibiotic.

Cephalotin (INN) or cephalothin (USAN) is a semisynthetic first generation cephalosporin having a broad spectrum of antibiotic activity that is administered parenterally.

Trade Name Cephalotin
Generic Cefalotin
Cefalotin Other Names Cefalothin, Cefalotin, Cefalotina, CĂ©falotine, Cefalotinum, Cephalothin, Cephalotin
Type
Formula C16H16N2O6S2
Weight Average: 396.438
Monoisotopic: 396.044977634
Protein binding

65-80%

Groups Approved, Investigational, Vet approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Cephalotin
Cephalotin

Uses

Cephalotin is a broad-spectrum cephalosporin antibiotic used for the treatment of serious bacterial infections in various locations, such as the urinary tract, skin, bone, and lower respiratory tract.

Used to prevent infection during surgery and to treat many kinds of infections of the blood, bone or joints, respiratory tract, skin, and urinary tract.

Cephalotin is also used to associated treatment for these conditions: Susceptible Bacterial Infections

How Cephalotin works

The bactericidal activity of cefalotin results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). The PBPs are transpeptidases which are vital in peptidoglycan biosynthesis. Therefore, their inhibition prevents this vital cell wall compenent from being properly synthesized.

Toxicity

Rat intravenous LD50 is 4000 mg/kg.

Food Interaction

No interactions found.

Half Life

30 minutes

Innovators Monograph

You find simplified version here Cephalotin

*** Taking medicines without doctor's advice can cause long-term problems.
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