Chlorprothixen Leciva Uses, Dosage, Side Effects and more

Chlorprothixen Leciva is a typical antipsychotic drug of the thioxanthene (tricyclic) class. Chlorprothixen Leciva exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors.

Chlorprothixen Leciva is a typical antipsychotic drug of the thioxanthine class. It has a low antipsychotic potency (half to 2/3 of chlorpromazine). Chlorprothixen Leciva has not thoroughly demonstrated an antidepressant or analgesic effect but it has demonstrated antiemetic effects. It is used in the treatment of nervous, mental, and emotional conditions. Improvement in such conditions is thought to result from the effect of the medicine on nerve pathways in specific areas of the brain. Chlorprothixen Leciva has a similar side effect profile to chlorpromazine, though allergic side effects and liver damage are less frequent.

Trade Name Chlorprothixen Leciva
Generic Chlorprothixene
Chlorprothixene Other Names Chlorprothixen, Chlorprothixene, Chlorprothixine, Chlorprotixen, Chlorprotixene, Chlorprotixine, Chlothixen
Type
Formula C18H18ClNS
Weight Average: 315.86
Monoisotopic: 315.0848485
Groups Approved, Experimental, Investigational, Withdrawn
Therapeutic Class
Manufacturer
Available Country Czech Republic, Slovakia
Last Updated: January 7, 2025 at 1:49 am

Uses

Chlorprothixen Leciva is a thioxanthene antipsychotic.

For treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occuring as part of bipolar disorders.

Chlorprothixen Leciva is also used to associated treatment for these conditions: Psychosis, Schizophrenia

How Chlorprothixen Leciva works

Chlorprothixen Leciva blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis.

Toxicity

Symptoms of overdose include difficulty in breathing (severe), dizziness (severe), drowsiness (severe), muscle trembling, jerking, stiffness, or uncontrolled movements (severe), small pupils, unusual excitement, and unusual tiredness or weakness (severe).

Food Interaction

Elimination Route

Incomplete bioavailability.

Half Life

8 to 12 hours

Innovators Monograph

*** Taking medicines without doctor's advice can cause long-term problems.
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