Chlorprothixine

Chlorprothixine Uses, Dosage, Side Effects, Food Interaction and all others data.

Chlorprothixine is a typical antipsychotic drug of the thioxanthene (tricyclic) class. Chlorprothixine exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors.

Chlorprothixine is a typical antipsychotic drug of the thioxanthine class. It has a low antipsychotic potency (half to 2/3 of chlorpromazine). Chlorprothixine has not thoroughly demonstrated an antidepressant or analgesic effect but it has demonstrated antiemetic effects. It is used in the treatment of nervous, mental, and emotional conditions. Improvement in such conditions is thought to result from the effect of the medicine on nerve pathways in specific areas of the brain. Chlorprothixine has a similar side effect profile to chlorpromazine, though allergic side effects and liver damage are less frequent.

Chlorprothixine
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Chlorprothixine
Generic	Chlorprothixene
Chlorprothixene Other Names	Chlorprothixen, Chlorprothixene, Chlorprothixine, Chlorprotixen, Chlorprotixene, Chlorprotixine, Chlothixen
Type
Formula	C₁₈H₁₈ClNS
Weight	Average: 315.86 Monoisotopic: 315.0848485
Groups	Approved, Experimental, Investigational, Withdrawn
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Chlorprothixine is a thioxanthene antipsychotic.

For treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occuring as part of bipolar disorders.

Chlorprothixine is also used to associated treatment for these conditions: Psychosis, Schizophrenia

How Chlorprothixine works

Chlorprothixine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis.

Toxicity

Symptoms of overdose include difficulty in breathing (severe), dizziness (severe), drowsiness (severe), muscle trembling, jerking, stiffness, or uncontrolled movements (severe), small pupils, unusual excitement, and unusual tiredness or weakness (severe).