Chlortetracycline Tai Yu
Chlortetracycline Tai Yu Uses, Dosage, Side Effects, Food Interaction and all others data.
Chlortetracycline is a tetracycline antibiotic, and historically the first member of this class to be identified. It was discovered in 1945 by the scientist, Benjamin Minge Duggar, working at Lederle Laboratories under the supervision of Yellapragada Subbarow. He discovered that this antibiotic was the product of an actinomycete strain he cultured and obtained from a soil sample from a field in Missouri. The organism was named Streptomyces aureofaciens due to its gold-hued color.
Tetracycline antibiotics are bacteriostatic agents which act to inhibit bacterial growth and reproduction .
| Trade Name | Chlortetracycline Tai Yu |
| Generic | Chlortetracycline + Triamcinolone Acetonide |
| Type | |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | Taiwan |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Chlortetracycline is the first tetracycline antibiotic most commonly used for veterinary purposes.
Used in the manufacuring of medicated animal feeds .
Chlortetracycline Tai Yu is also used to associated treatment for these conditions: Eye and eyelid infections, Pyoderma, Wound Infections, Corticosteroid-responsive dermatoses
How Chlortetracycline Tai Yu works
Chlortetracycline, like other tetracyclines, competes for the A site of the bacterial ribosome . This binding competes with tRNA carrying amino acids preventing the addition of more amino acids to the peptide chain. This inhibition of protein synthesis ultimately inhibits growth and reproduction of the bacterial cell as necessary proteins cannot be synthesized.
Toxicity
The acute oral LD50 in mice is 2314mg/kg .The most common adverse effects of tertacylines are gastrointestinal disturbances, and staining of teeth and bone. Some occurences of dental hypoplasia and bone deformity have been noted . In pregnant women tetracyclines may produce hepatotoxicity.
Volume of Distribution
Chlortetracycline has a volume of distribution of 100 liters .
Elimination Route
Chortetracycline reaches peak plasma concentation in about 3 hours . Its oral bioavailability is 25-30%.
Half Life
The half-life of Chlortetracycline is 5.6 hours .
Elimination Route
Chlortetracycline is mainly eliminated in feces . Renal function does not appear to affect the rate of elimination.
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