Chorionic Gonadotrophin

Chorionic Gonadotrophin Uses, Dosage, Side Effects, Food Interaction and all others data.

Human chorionic gonadotropin (HCG), a polypeptide hormone produced by the human placenta. Endogenously produced HCG interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy. This allows the corpus luteum to continuously secrete the hormone progesterone during the first trimester, which is required for maintenance of the uterus and prevents menstruation. In males, HCG also stimulates the production of gonadal steroid hormones by stimulating the interstitial cells (Leydig cells) of the testis to produce androgens.

HCG is composed of an alpha and a beta sub-unit. The alpha sub-unit is essentially identical to the alpha sub units of the human pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), as well as to the alpha sub-unit of human thyroid-stimulating hormone (TSH), while the beta sub units of these hormones differ in amino acid sequence. As a drug product, chorionic gonadotropin is a highly purified pyrogen-free preparation obtained from the urine of pregnant females.

The action of HCG is virtually identical to that of pituitary LH, although HCG appears to have a small degree of FSH activity as well. It stimulates production of gonadal steroid hormones by stimulating the interstitial cells (Leydig cells) of the testis to produce androgens and the corpus luteum of the ovary to produce progesterone.

Chorionic Gonadotrophin
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Uses during Pregnancy
Uses during Breastfeeding
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Trade Name	Chorionic Gonadotrophin
Generic	Chorionic Gonadotropin (Human)
Chorionic Gonadotropin (Human) Other Names	Chorionic gonadotrophin, Chorionic gonadotropin, Gonadotropin, Chorionic, Gonadotropin,chorionic, h-HCG, hCG, Human chorionic gonadotropin, Human menopausal gonadotropin, Human menopausal gonadotropin (urine derived), Human-chorionic gonadotropin, Urinary hCG
Type
Groups	Approved, Vet approved
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Last Updated:	September 19, 2023 at 7:00 am

Uses

Chorionic Gonadotrophin is a naturally-occurring hormone produced during human placenta used for the treatment of prepubertal cryptorchidism and hypogonadotropic hypogonadism in selected males, and induction of pregnancy in selected infertile women.

For the treatment of prepubertal cryptorchidism (not due to anatomical obstruction), for the treatment of selected cases of hypogonadotropic hypogonadism (hypogonadism secondary to a pituitary deficiency) in males and for the induction of ovulation and pregnancy in the anovulatory, infertile woman in whom the cause of anovulation is secondary and not due to primary ovarian failure, and who has been appropriately pretreated with human menotropins.

Chorionic Gonadotrophin is also used to associated treatment for these conditions: Idiopathic Hypogonadotropic Hypogonadism, Undescended Testis, Secondary Hypogonadotrophic hypogonadism, Ovulation induction therapy, Stimulation of spermatogenesis therapy