Chromostat
Chromostat Uses, Dosage, Side Effects, Food Interaction and all others data.
Adrenochrome Monosemicarbazone is a haemostatic with a rapid onset of action. It contains a water soluble form of adrenochrome monosemicarbazone, a stable derivative of adrenochrome as the active substance. Adrenochrome is an oxidation product of adrenaline; it reduces normal and pathologic bleeding time by decreasing capillary permeability. It produces capillary haemostatis without exerting any of the adrenergic actions on respiration or cardiovascular system. Thus, despite its adrenaline like action on small blood vessels, does not give rise to the general systemic effects of sympathomimetic drugs.
| Trade Name | Chromostat |
| Generic | Monosemicarbazone Adrenochrome |
| Weight | 500mg |
| Type | Injection, Tablet |
| Therapeutic Class | Anti-fibrinolytic drugs |
| Manufacturer | Life Pharma |
| Available Country | India |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Chromostat is used for the prevention and treatment of surgical and non-surgical capillary bleedings.
Dosage
Chromostat dosage
For the prevention and treatment of capillary bleedings, accordingly to the severity of the case, 4-12 tablets divided over the day, preferably one hour before meals. Prior to surgery, medication is started on the preceding evening, either orally or by intramuscular or subcutaneous injection of usually 1.5-5 mg. In addition, an injection is given about half an hour before the surgical intervention.
Injection solution should be administered by intramuscular or subcutaneous route; in emergency cases the injections may be given intravenously. The tablets should be taken orally.
Side Effects
No adverse reactions have been reported at the recommended dosages.
Precaution
Because of the content of diprophylline (90 mg/ml), the dosage of the 5 mg/ml injection preparation to premature babies, infants and young children should not exceed 0.3 ml.
Interaction
No specific drug interaction has been demonstrated.
Pregnancy & Breastfeeding use
During pregnancy, the benefits of the use of Chromostat should be weighed against the possible hazards of the foetus.
Contraindication
There are no known contraindications.
Storage Condition
Store in a cool (in between 2°-25°C), dry place & protect from light. Keep out of the reach of children.
Innovators Monograph
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