Ciclo-scot

Ciclo-scot Uses, Dosage, Side Effects, Food Interaction and all others data.

A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.

This compound is needed for good nerve conduction throughout the CNS (central nervous system) as it is a precursor to acetylcholine (ACh). Ciclo-scot is also needed for gallbladder regulation, liver function and lecithin (a key lipid) formation. Ciclo-scot also aids in fat and cholesterol metabolism and prevents excessive fat build up in the liver. Ciclo-scot has been used to mitigate the effects of Parkinsonism and tardive dyskinesia. Ciclo-scot deficiencies may result in excessive build-up of fat in the liver, high blood pressure, gastric ulcers, kidney and liver dysfunction and stunted growth.

Trade Name Ciclo-scot
Availability Discontinued
Generic Choline
Choline Other Names Bilineurine, N-trimethylethanolamine, N,N,N-trimethylethanol-ammonium, trimethylethanolamine, Vitamin J
Weight 1.5%w/w
Type Liquid
Formula C5H14NO
Weight Average: 104.1708
Monoisotopic: 104.107539075
Groups Approved, Nutraceutical
Therapeutic Class
Manufacturer Scotmann Pharmaceuticals
Available Country Pakistan
Last Updated: September 19, 2023 at 7:00 am
Ciclo-scot
Ciclo-scot

Uses

Ciclo-scot is a nutrient found in a wide variety of vitamins including pre-natal formulations.

For nutritional supplementation, also for treating dietary shortage or imbalance

Ciclo-scot is also used to associated treatment for these conditions: Nutritional supplementation

How Ciclo-scot works

Ciclo-scot is a major part of the polar head group of phosphatidylcholine. Phosphatidylcholine's role in the maintenance of cell membrane integrity is vital to all of the basic biological processes: information flow, intracellular communication and bioenergetics. Inadequate choline intake would negatively affect all these processes. Ciclo-scot is also a major part of another membrane phospholipid, sphingomyelin, also important for the maintenance of cell structure and function. It is noteworthy and not surprising that choline deficiency in cell culture causes apoptosis or programmed cell death. This appears to be due to abnormalities in cell membrane phosphatidylcholine content and an increase in ceramide, a precursor, as well as a metabolite, of sphingomyelin. Ceramide accumulation, which is caused by choline deficiency, appears to activate Caspase, a type of enzyme that mediates apoptosis. Betaine or trimethylglycine is derived from choline via an oxidation reaction. Betaine is one of the factors that maintains low levels of homocysteine by resynthesizing L-methionine from homocysteine. Elevated homocysteine levels are a significant risk factor for atherosclerosis, as well as other cardiovascular and neurological disorders. Acetylcholine is one of the major neurotransmitters and requires choline for its synthesis. Adequate acetylcholine levels in the brain are believed to be protective against certain types of dementia, including Alzheimer's disease.

Toxicity

Oral rat LD50: 3400 mg/kg

Food Interaction

No interactions found.

Innovators Monograph

You find simplified version here Ciclo-scot

http://classyfire.wishartlab.com/tax_nodes/C0000000
http://classyfire.wishartlab.com/tax_nodes/C0004707
http://classyfire.wishartlab.com/tax_nodes/C0000278
http://classyfire.wishartlab.com/tax_nodes/C0000503
http://classyfire.wishartlab.com/tax_nodes/C0001012
http://classyfire.wishartlab.com/tax_nodes/C0004225
http://classyfire.wishartlab.com/tax_nodes/C0001897
http://classyfire.wishartlab.com/tax_nodes/C0000286
http://classyfire.wishartlab.com/tax_nodes/C0004557
http://classyfire.wishartlab.com/tax_nodes/C0003865
http://classyfire.wishartlab.com/tax_nodes/C0004150
http://classyfire.wishartlab.com/tax_nodes/C0003609
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:15354
http://www.genome.jp/dbget-bin/www_bget?cpd:C00114
http://metacyc.org/META/new-image?type=COMPOUND&object=CHOLINE
http://www.hmdb.ca/metabolites/HMDB0000097
http://www.genome.jp/dbget-bin/www_bget?drug:D07690
http://www.genome.jp/dbget-bin/www_bget?cpd:C00114
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=305
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46508132
https://www.chemspider.com/Chemical-Structure.299.html
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026220
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=2449
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=15354
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL920
https://zinc.docking.org/substances/ZINC000003079337
http://www.pharmgkb.org/drug/PA448976
https://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/CHT
http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/cho_0283.shtml
https://en.wikipedia.org/wiki/Choline
*** Taking medicines without doctor's advice can cause long-term problems.
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