citanest
citanest Uses, Dosage, Side Effects, Food Interaction and all others data.
A synthetic nonapeptide comprising cysteinyl, phenylalanyl, phenylalanyl, glutaminyl, asparaginyl, cysteinyl, prolyl, lysyl, and glycinamide residues in sequence, with a disulfide bridge joining the two cysteine residues. Its antidiuretic effects are less than those of vasopressin. It is a non-catecholamine vasoconstrictor used in local anaesthetic injections for dental use, and is an ingredient of preparations that have been used for treatment of pain and inflammation of the mouth.
Felypressin is a synthetic analog of lypressin or vasopressin with a greater vasoconstrictor activity than antidiuretic action. It is used primarily as a hemostatic.
| Trade Name | citanest |
| Generic | Prilocaine Hydrochloride + Felypressin |
| Weight | 3%, |
| Type | Solution |
| Therapeutic Class | |
| Manufacturer | Dentsply Limited, Aspen, Astra Zeneca |
| Available Country | Saudi Arabia, United Kingdom, Netherlands, |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
For use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential.
How citanest works
Felypressin binds to the vasopressin receptor V1a. This causes contraction of the smooth muscle in the vascular bed, especially capillaries, small arterioles and venules.
Innovators Monograph
You find simplified version here citanest
