Citrucel Clear Mix
Citrucel Clear Mix Uses, Dosage, Side Effects, Food Interaction and all others data.
Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3, however more typical values are 1.3 2.6. Methyl cellulose is a hydrophilic white powder in pure form and dissolves in cold (but not in hot) water, forming a clear viscous solution or gel. It is available under a variety of trade names as a treatment for constipation. Like cellulose, it is not digestible, not toxic, and not allergenic
It increases the bulk in your stool, an effect that helps to cause movement of the intestines. It also works by increasing the amount of water in the stool, making the stool softer and easier to pass.
| Trade Name | Citrucel Clear Mix |
| Availability | Rx and/or OTC |
| Generic | Methylcellulose |
| Methylcellulose Other Names | Cellulose methyl, cellulose methyl ether, Cellulose methylate, Methyl cellulose, methylated cellulose, Methylcellulose, Methylcellulosum, Metilcelulosa |
| Related Drugs | MiraLAX, Colace, docusate, Linzess, bisacodyl, senna |
| Weight | 2g/19g, 500mg |
| Type | Oral powder for reconstitution, oral tablet |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | United States |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Citrucel Clear Mix is a compound used as a bulk forming laxative and is not an approved medication.
Solutions containing methyl cellulose are used as substitute for tears or saliva if the natural production of these fluids is disturbed. It is also used or constipation, diverticulosis, hemorrhoids and irritable bowel syndrome. Used in the manufacture of capsules in nutritional supplements. Its edible and nontoxic properties provide a vegetarian alternative to the use of gelatin.
Citrucel Clear Mix is also used to associated treatment for these conditions: Constipation, Dry Eye Syndrome (DES), Eye disinfection
How Citrucel Clear Mix works
Citrucel Clear Mix absorbs water in the gastrointestinal lumen thereby increasing the bulk of the stool. This leads to distension and stimulation of peristalsis. The ability of methylcellulose to absorb water may contribute to its efficacy in the management of diarrhea by once again increasing the bulk and consistency of the stool.
Toxicity
Organism: Mouse Test type: LD50 Route : Intraperitoneal Reported Dose: 275gm/kg ( 275000mg/kg) Toxic Effect: Details of toxic effects not reported other than lethal dose value
Organism: Mouse Test type: LDLo Route : Intravenous Reported Dose: 1gm/kg ( 1000mg/kg) Toxic Effect: Details of toxic effects not reported other than lethal dose value
Food Interaction
- Take with a full glass of water.
[Moderate] ADJUST DOSING INTERVAL: Bulk-forming laxatives such as guar gum, psyllium, polycarbophil, or methylcellulose may affect the bioavailability of concomitantly administered substances due to their effect on the rate of gastrointestinal transit and gastric emptying.
MANAGEMENT: In general, oral medications should be administered at least 2 hours before or 2 hours after dosing of the bulk-forming laxative.
Citrucel Clear Mix Drug Interaction
Unknown: aspirin, aspirin, diphenhydramine, diphenhydramine, calcium / vitamin d, calcium / vitamin d, ubiquinone, ubiquinone, omega-3 polyunsaturated fatty acids, omega-3 polyunsaturated fatty acids, multivitamin, multivitamin, acetaminophen, acetaminophen, cyanocobalamin, cyanocobalamin, ascorbic acid, ascorbic acid, cholecalciferol, cholecalciferol
Citrucel Clear Mix Disease Interaction
Major: intestinal obstruction, inflammatory bowel disease, intestinal obstruction disordersModerate: renal dysfunction
Volume of Distribution
accumulation in liver, spleen, lymph nodes, kidney, and vascular walls.
Elimination Route
Cellulose derivatives considered in this report are virtually unabsorbed and little or no degradation of absorbed and little or no degradation of absorbable products occurs in the human digestive tract. In humans, virtually 100 percent of orally ingested methyl cellulose can be recovered in the feces withihn four days, indicating that absorption does not occur.
Half Life
4.2 minutes
Elimination Route
When swallowed they are not absorbed to any appreciable degree and appear unchanged in feces.
Innovators Monograph
You find simplified version here Citrucel Clear Mix
