Clif F Tube
Clif F Tube Uses, Dosage, Side Effects, Food Interaction and all others data.
Avobenzone is dibenzoyl methane derivative. It is oil soluble ingredient. Avobenzone has the ability to absorb ultraviolet light over wider range of wavelengths. It is included in many commercially available sunscreens which are used as wide spectrum sunscreens. Avobenzone is very sensitive to light, to increase its stability and duration of action, photostablizers are added in the sunscreen product. Avobenzone has an absorption maximum of 357 nm. Sunscreens containing avobenzone is indicated for providing protection from the sun. In addition to limiting the skin's exposure to the sun, using sunscreen agents may help reduce long-term sun damage such as premature aging of the skin and skin cancer.
Glycerin is a hyperosmotic laxative, given rectally, which usually produces a bowel movement within 15 minutes to 1 hour. Hyperosmotic laxatives encourage bowel movements by drawing water into the bowel from surrounding tissues. This produces a softer stool mass and increased bowel action. These products are used for fast, predictable relief of occasional constipation.
Glycerin is commonly classified as an osmotic laxative but may act additionally or alternatively through its local irritant effects; it may also have lubricating and fecal softening actions. Glycerin suppositories usually work within 15 to 30 minutes.
Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation dissipated by sunlight, and to minimize skin damage from prolonged sun exposure. Octocrylene is also often combined with avobenzone, another common sunscreen ingredient often appearing on ingredient labels. Because of its effectiveness, the chemical has been approved across the globe for use in cosmetics and skin care products, but the concentrations of this ingredient are usually limited to no more than 10 or 12 percent. However, the use of this chemical doesn’t just stop with sunscreen for face and arms, but can extend to a variety of other products, like hair spray, tannin oil, BB cream, conditioner, and CC cream, among others. Octocrylene may cause contact and photocontact allergy.
Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone.
A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Zinc oxide is used to treat or prevent minor skin irritations such as burns, cuts, poison ivy, poison oak, poison sumac, and diaper rash. It is also used as a sunscreen.
Zinc oxide has astringent, soothing and protective properties and is used in topical preparations for eczema, slight excoriations, wounds and haemorrhoids. It also reflects ultraviolet radiation and can be used as a physical sunscreen.
| Trade Name | Clif F Tube |
| Generic | Aloe Vera + Avobenzone + Glycerin + Liquid Paraffin + Octocrylene + Octyl Methoxycinnamate + Oxybenzone + Petroleum Jelly + Propylene Glycol + Stearyl Alcohol + Zinc Oxide |
| Weight | 1%w/v |
| Type | Face Wash |
| Therapeutic Class | |
| Manufacturer | Cubit Healthcare |
| Available Country | India |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Avobenzone is a sunscreen agent found in sunscreens that absorbs UV rays.
Sun protection factor, added in the sunscreen products for its wide spectrum ultraviolet absorption properties.
For the relief of occasional constipation
Octocrylene is a sunscreen agent found in sunscreens that absorbs UV rays.
In the US, Octocrylene has been evaluated by the FDA and is considered safe for use up to 10% in the formula. Similarly, the EU allows its use up to 10% in a formula while Health Canada allows a maximum use level of 12%.
Oxybenzone is a sunscreen agent found in sunscreens that absorbs UV rays.
Used as an ingredient in sunscreen and other cosmetics.
Zinc Oxide helps to To treat or prevent skin irritations (e.g., burns, bed sore, cuts, poison ivy, diaper rash). Protects chafed skin due to diaper rash and helps seal out wetness.
Clif F Tube is also used to associated treatment for these conditions: SunburnCold Sore, Constipation, Dry Mouth, Dry Skin, Dry throat, Edema of the cerebrum, Hypertension Intracranial, Occasional Constipation, Ocular Discomfort, Ocular Hypertension, Ocular Irritation, Skin Infections, Sore Throat, Mouth soreness, Ocular burning, Bowel preparation therapy, Topical Antisepsis, Skin protectionSunburnSunburnDry Eyes, Ocular Irritation, Eye lubrication, Scalp HealthAcute Wounds, Burns first degree, Burns second degree, Dermatitis, Eczematous, Diaper Rash, Herpes Labialis, Injuries to the Nipple (Fissures and Cracks) Resulting Breastfeeding, Intertrigo, Pain, Pruritus, Sensitive Skin, Skin Irritation, Skin candida, Sunburn, Wounds, Chafing, Damaged skin, Dry, cracked skin, Facial rash, Heat rash, Superficial Wounds, Watery skin lesions, Astringent, Nutritional supplementation
How Clif F Tube works
It blocks UVA I, UVA II, and UVB wavelengths, thereby limiting the impact of UV rays on skin. Diminish the penetration of ultraviolet (UV) light through the epidermis by absorbing UV radiation within a specific wavelength range. The amount and wavelength of UV radiation absorbed are affected by the molecular structure of the sunscreen agent.
When administered rectally, glycerin exerts a hygroscopic and/or local irritant action, drawing water from the tissues into the feces and reflexively stimulating evacuation. Glycerin decreases intraocular pressure by creating an osmotic gradient between the blood and intraocular fluid, causing fluid to move out of the aqueous and vitreous humors into the bloodstream.
Octocrylene is an effective oil soluble liquid UV‐B filter. It has excellent dissolving properties for crystalline UV filters. Due to its outstanding photostability it is used as photostabilizer. Conjugated acrylate portion absorbs UVB and short-wave UVA (ultraviolet) rays with wavelengths in the range of 280-320 nm which protects the skin from direct DNA damage. The ethylhexanol portion is a fatty alcohol, which functions as an emollient due to it's hydrophobicity.
Oxybenzone absorbs UV-A ultraviolet rays, preventing them from reaching the skin.
It acts by providing a physical barrier to prevent skin irritation and help heal damaged skin.
Dosage
Clif F Tube dosage
Children under 2 years: Consult a physician.
Children (2 to 6 years): only 1 Glycerin 1.15 suppository per 24 hours or as directed by a physician.
Adults and Children (From 6 years): only 1 Glycerin 2.30 suppository per 24 hours or as directed by a physician
Insert suppository well up into rectum. Suppository need to melt completely to produce laxative action.
Apply thin layer topically every 8 hourly. Change wet and soiled diapers, promptly cleans the diaper area, allow to dry and apply ointment liberally as often as necessary, with each diaper change, especially at bedtime or any time when exposure to wet diapers may be prolonged.
Side Effects
Glycerin when used rectally may cause rectal discomfort or a burning sensation
Usually well tolerated. Extremely low frequency of hypersensitivity reaction.
Toxicity
A minimum toxic dose has not been established. Significant toxicity is not expected
Glycerol has very low toxicity when ingested ; Rat LD50 (oral)-12600mg/kg Mice LD50 (oral )-4090mg/kg Human TDLo (oral) - 1428mg/kg
Octocrylene is one of those ingredients that can be absorbed into the skin and some studies have shown that it may promote generation of potentially harmful free radicals when exposed to light. Since free radicals can damage DNA, there is concern that this ingredient might have contributed to an increased incidence of melanoma in sunscreen-users compared to non-users.
Acute oral toxicity (LD50): 7950 mg/kg [Mouse].
Precaution
For external use only. Avoid contact with the eyes. Stop use and ask a doctor if condition worsens or does not improve within 7 days. Keep out of the reach of children. If swallowed, get medical help or contact a poison control center right away
Volume of Distribution
Glycerin is distributed throughout the blood. Although glycerin generally does not appear in ocular fluids, it may enter the orbital sac when the eye is inflamed, with a consequent decrease in osmotic effect.
Ecamsule is only used topically, it not absorbed.
Intended for local use only, no systemic absorption.
Elimination Route
Well absorbed orally, poorly absorbed rectally. Studies in humans and animals indicate glycerol is rapidly absorbed in the intestine and the stomach
Ecamsule is used topically, it not absorbed or metabolized.
No significant percutaneous absorption from topically applied zinc oxide.
Half Life
30 - 45 minutes
Ecamsule is only used topically, it does not have half life
Intended for local use only, no systemic absorption.
Clearance
Ecamsule is used topically, it not absorbed or metabolized.
Intended for local use only, no systemic absorption.
Elimination Route
Approx 7-14% of dose is excreted unchanged in the urine within 2.5 hr.
Ecamsule is used topically, it not absorbed.
In vivo studies show oxybenzone is abosorbed transdermally (through the skin) and is excreted in the urine.
Intended for local use only, no systemic absorption.
Pregnancy & Breastfeeding use
Pregnancy category C. There are no controlled data in human pregnancy
This medication should be used with precautions only if clearly needed during pregnancy or while breast feeding
Contraindication
Sensitivity to the ingredients. Do not use unless the patient to be treated is, in fact, constipated.
Known hypersensitivity to any component of the preparation
Acute Overdose
No overdose related problem is yet reported.
Storage Condition
Store below 25° C. Protect from moisture.
keep in a cool and dry place, away from light.
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