ClinOleic
ClinOleic Uses, Dosage, Side Effects, Food Interaction and all others data.
Oil extracted from olives . Consists primarily of the glycerides of the fatty acids linoleic, oleic and palmitic. Used as a source of fatty acids in total parenteral nutrition and as an additive in some cosmetic products .
Provides a source of calories and fatty acids .
| Trade Name | ClinOleic |
| Generic | olive oil + refined + soya bean oil + refined |
| Type | Emulsion lemak |
| Therapeutic Class | |
| Manufacturer | Baxter Healthcare Ltd, Baxter Sa, Kalbe Farma |
| Available Country | United Kingdom, Netherlands, Portugal, Indonesia, |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
For use in adults as a source of calories and fatty acids in total parenteral nutrition . Sometimes used as an additive in cosmetic products.
ClinOleic is also used to associated treatment for these conditions: Nutritional supplementation, Total parenteral nutrition therapy
How ClinOleic works
Fatty acids act as a substrate in energy production through beta-oxidation as well as important components of cell membrane structures and prescursors for bioactive molecules like prostaglandins .
Toxicity
Fat overload sydrome is the primary form of toxicity characterized by a sudden deterioration in the patient's condition accompanied by fever, anemia, leukopenia, thrombocytopenia, coagulation disorders, hyperlipidemia, liver fatty infiltration, deteriorating liver function, and central nervous system manifestations such as coma . The precise cause of this is unclear. While it is most likely to occur during overdosage of lipids some occurences have been reported when lipids are administered appropriately. Intraperitoneal LD50 in mice of >50g/kg and intravenous LD50 in rats of 1320mg/kg .
Innovators Monograph
You find simplified version here ClinOleic
