CNS-5161

CNS-5161 Uses, Dosage, Side Effects, Food Interaction and all others data.

CNS 5161 is a blocker of the NMDA ion channel and has completed Phase IIa proof of concept clinical trials as a novel compound for the treatment of neuropathic pain.

Trade Name CNS-5161
Generic CNS-5161
Type
Formula C16H18ClN3S2
Weight Average: 351.917
Monoisotopic: 351.063066678
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
CNS-5161
CNS-5161

Uses

Investigated for use/treatment in migraine and cluster headaches, neuropathy (diabetic), and pain (acute or chronic).

How CNS-5161 works

CNS 5161 is a selective and high affinity N-methyl-D-aspartate (NMDA) receptor antagonist with preferential binding to the activated form of the receptor. CNS 5161 also penetrates the brain well and can be used to label selectively brain NMDA receptors in vivo. A radioactive form of CNS 5161 may be used as an agent to monitor NMDA receptors in the human brain using Positron Emission Tomography ("PET") and "the significance of a selective, validated radiopharmaceutical agent suitable for detecting widespread as well as highly localized changes in the NMDA receptor in the living brain cannot be exaggerated".

Innovators Monograph

You find simplified version here CNS-5161

*** Taking medicines without doctor's advice can cause long-term problems.
Share