Colamin Tablet 500 mcg
Colamin Tablet 500 mcg Uses, Dosage, Side Effects, Food Interaction and all others data.
Colamin Tablet 500 mcg is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.
| Trade Name | Colamin Tablet 500 mcg |
| Generic | Mecobalamin |
| Mecobalamin Other Names | Co-methylcobalamin, MeCbl, Mecobalamin, Mecobalamina, Mecobalaminum, Methyl vitamin B12, Methyl(III)cobalamin, Methylcobalamin |
| Weight | 500 mcg |
| Type | Tablet |
| Formula | C63H91CoN13O14P |
| Weight | Average: 1344.3823 Monoisotopic: 1343.587806391 |
| Groups | Approved, Investigational |
| Therapeutic Class | Drugs for Megaloblastic Anemia |
| Manufacturer | Rangs Pharmaceuticals Ltd. |
| Available Country | Bangladesh |
| Last Updated: | October 19, 2023 at 6:27 am |
Uses
Colamin Tablet 500 mcg is used for-
- Peripheral Neuropathies
- Diabetic Neuropathy
- Verteberal Syndrome
- Nerve Compression Syndrome
- Multiple sclerosis
- Amyotrophic lateral sclerosis
- Parkinson’s disease
- Alzheimer’s disease
- Diabetic retinopathy
- Entrapment neuropathy
- Drug induced neuropathy
- Megaloblastic anemia due to Vitamin B12 deficiency
Colamin Tablet 500 mcg is also used to associated treatment for these conditions: Vitamin B12 Deficiency, Nutritional supplementation
Dosage
Colamin Tablet 500 mcg dosage
Tablet: The usual adult dosage is one 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms.
Injection:
- Peripheral neuropathies: The usual adult dosage is one ampoule equivalent to 500 mcg of Colamin Tablet 500 mcg, administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms.
- Megaloblastic anemia: The usual adult dosage is one ampoule equivalent to 500 mcg of Colamin Tablet 500 mcg, administered intramuscularly or intravenously three times a week. After about two months of administration, dosage should be changed to one ampoule equivalent to 500 mcg of Colamin Tablet 500 mcg every one to three months as maintenance therapy
Side Effects
Generally Colamin Tablet 500 mcg is well tolerated. However, a few side effects like GI discomfort (including anorexia, nausea or diarrhea) & rash may be seen after administration of Colamin Tablet 500 mcg.
Precaution
The medicine should not be used for months if there is no response at all after its use for a certain period of time.
Interaction
Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine. Reduced serum concentrations with oral contraceptives. Reduced effects in anaemia with parenteral chloramphenicol.
Food Interaction
No interactions found.Pregnancy & Breastfeeding use
Not recommended during pregnancy & lactation.
Contraindication
Hypersensitivity to any component of this product.
Special Warning
Use in children: Not recommended.
Storage Condition
Oral: Store at room temperature. Protect from moisture and light.
Parenteral: Store at room temperature. Do not expose to direct light.
Innovators Monograph
You find simplified version here Colamin Tablet 500 mcg
FAQ
What is Colamin Tablet 500 mcg used for?
Colamin Tablet 500 mcg is used to treat vitamin B12 deficiency.
How safe is Colamin Tablet 500 mcg?
Colamin Tablet 500 mcg is considered likely safe when used appropriately.
How does Colamin Tablet 500 mcg work?
Colamin Tablet 500 mcg works by functioning in the production of a compound called myelin, which covers and protect nerve fibers.
What are the common side effects of Colamin Tablet 500 mcg?
Common side effects of Colamin Tablet 500 mcg are include:
- Nausea.
- Vomiting.
- Diarrhea.
- Loss of appetite.
- Headache.
Is Colamin Tablet 500 mcg safe during pregnancy?
Pregnancy There are no data available for Colamin Tablet 500 mcg to be used in pregnant women.
Is Colamin Tablet 500 mcg safe during breastfeeding?
There are no data available for Colamin Tablet 500 mcg to be used in lactating women.
Can I drink alcohol with Colamin Tablet 500 mcg?
No interactions were found between Alcohol and Colamin Tablet 500 mcg. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Can I take Colamin Tablet 500 mcg daily?
The recommended dose is 500 mcg three times daily or 1500 mcg daily. Most generic vitamins contain cyanocobalamin, which may not be as effective or as beneficial.
How much Colamin Tablet 500 mcg should I take?
The general recommendation for adults is 2.4 mcg. Older adults, as well as pregnant and breastfeeding women, require higher doses.
Should I take Colamin Tablet 500 mcg on an empty stomach?
It is a well-known medical fact that water-soluble vitamins are better absorbed on an empty stomach. So, the usual time of taking Colamin Tablet 500 mcg will be in the morning as the first dose, half an hour before lunch, and 2 hours post a meal.
How long does Colamin Tablet 500 mcg take to work?
With brisk development of new red blood cells, a response is typically seen within 48 to 72 hours. Colamin Tablet 500 mcg supplies have reached normal levels,Colamin Tablet 500 mcg injections will be required every one to three months to avoid the return of symptoms.
How long does Colamin Tablet 500 mcg supplements stay in my system?
Other studies have shown that Colamin Tablet 500 mcg has a half-life of around six days in the blood, which means that it would take six days before half of the administered amount is excreted from the body
Can Colamin Tablet 500 mcg damage my liver?
There is no evidence that the other B vitamins, in physiologic or even super-physiologic high doses cause liver injury or jaundice.
What are the symptoms of high Colamin Tablet 500 mcg levels?
The study found that high doses of these Colamin Tablet 500 mcg were actually harmful.
Can Colamin Tablet 500 mcg cause kidney stones?
Colamin Tablet 500 mcg have not been shown to be harmful to people with kidney stones.
How long Colamin Tablet 500 mcg can be taken?
Colamin Tablet 500 mcg for 2-4 weeks is associated with better outcome in nerve conduction velocity and neuropathic symptoms.
Who should not take Colamin Tablet 500 mcg?
You should not use Colamin Tablet 500 mcg if you are allergic to Colamin Tablet 500 mcg or cobalt. Tell your doctor if you have ever had Leber's disease or other form of optic nerve damage,an iron or folic acid deficiency.
What happens if I miss a dose of Colamin Tablet 500 mcg?
Use Colamin Tablet 500 mcg as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.
Can I overdose on Colamin Tablet 500 mcg?
You cannot overdose on Colamin Tablet 500 mcg because any excess you simply pee out. If you get Colamin Tablet 500 mcg shots, you may experience side effects like dizziness, nausea, and fatigue.
