Comforas Uses, Dosage, Side Effects and more

Comforas is a sulfated pentosyl polysaccharide with heparin-like properties.

Comforas sodium is a low molecular weight heparin-like compound. It has anticoagulant and fibrinolytic effects.

Trade Name Comforas
Generic Pentosan polysulfate
Pentosan polysulfate Other Names Pentosan polysulfate, Pentosan sulfuric polyester, Pentosane polysulfate, Pentosani polysulfas, Pentosano polisulfato, Pentosanpolysulfat
Weight 100mg
Type Capsule
Formula C10H18O21S4
Weight Average: 602.497
Monoisotopic: 601.922340398
Groups Approved
Therapeutic Class
Manufacturer West-coast Pharmaceutical Works Ltd
Available Country India
Last Updated: January 7, 2025 at 1:49 am

Uses

Comforas is a sulfated pentosyl polysaccharide used to treat bladder pain and discomfort due to interstitial cystitis.

For the relief of bladder pain or discomfort associated with interstitial cystitis.

Comforas is also used to associated treatment for these conditions: Cystitis interstitial

How Comforas works

Comforas is a polymer of xylose hydrogen sulfate and contains two sulfate groups per carbohydrate monomer. It binds Fibroblast growth factors (FGFs) as well as other heparin-binding growth factors. It has been shown to interact also with the heparin-binding site of FGFR-1. It inhibits the growth of SW13 adrenocortical cells transfected with FGF-4 and tumorigenicity of MCF-7 breast carcinoma cells transfected with FGF-1 or FGF-4.

Food Interaction

Elimination Route

Slow

Half Life

4.8 hours

Innovators Monograph

*** Taking medicines without doctor's advice can cause long-term problems.
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