Cophylac

Cophylac Uses, Dosage, Side Effects, Food Interaction and all others data.

Normethadone is used as an opioid antitussive in combination with Oxilofrine. It is marketed in Canada by Valeant under the tradename Cophylac.

Normethadone is an opioid which suppresses coughing by central and peripheral mechanisms .

Table Of contents

• Cophylac
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Cophylac
Generic	normethadone + hydroxyephedrine
Type
Therapeutic Class
Manufacturer
Available Country	Canada, United States,
Last Updated:	September 19, 2023 at 7:00 am

Uses

Normethadone is an opioid antitussive used to treat a cough associated with inflamed mucosa.

For use in the treatment of cough when other less potent treatments have failed .

How Cophylac works

Normethadone activates central opioid receptors in the medulla to supress the cough reflex . It also likely activates peripheral opioid receptors to inhibit signalling by irritant receptors of the airway.

Toxicity

The toxic effects of normethadone are similar to those of other opioids. It can produce respiratory depression, depression of central nervous system function, and constipation .

Innovators Monograph

You find simplified version here Cophylac