Cornigel Eye
Cornigel Eye Uses, Dosage, Side Effects, Food Interaction and all others data.
Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments .
Lanolin is the purified, secreted product of the sheep sebaceous glands . Lanolin primarily consists of long-chain waxy esters, or sterol esters, that lack glycerides. For this reason, it is also called wool wax or wool grease. Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. Its hydrophobic properties can help protect skin against infections or skin irritation, as it helps seal in moisture that is already present in the skin .
Lanolin is used as an active ingredient in over the counter topical products such as ointments, lubricants, lotions and facial cosmetics. Lanolin is also frequently used in protective baby skin treatment and for sore nipples in breastfeeding mothers , .
Mineral oil, or paraffin oil, is a mixture of higher alkanes from a mineral source, such as petroleum. Petroleum mineral oil is manufactured from crude oils by vacuum distillation to produce several distillates and a residual oil that are then further refined. During the modern refining process, aromatics are reduced by solvent extraction, catalytic hydrotreating, or hydrocracking. Unrefined or mildly treated mineral oils are classified as Group 3 carcinogens by the World Health Organizations, as chronic exposure to these aromatics including alkylated polycyclic aromatic compounds (PAC) can lead to skin cancer.
Mineral oil is a common ingredient in baby lotions, cold creams, ointments and cosmetics to treat and prevent dry, rough, scaly, itchy skin and minor skin irritations. It is also used as a mild laxative for human or veterinary uses.
Mineral oil blocks the loss of water from the skin allowing greater hydration of the epidermis .
| Trade Name | Cornigel Eye |
| Generic | White Soft Paraffin + Mineral Oil + Lanolin |
| Weight | 57.3% |
| Type | Ointment |
| Therapeutic Class | |
| Manufacturer | Micro Labs |
| Available Country | India |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Lanolin is an ingredient used in skin care products to relieve irritation.
Used as a skin protectant, and to relieve dryness and irritation of the skin , . Helps prevent and treat diaper dermatitis .
Mineral oil is not considered an active pharmacological ingredient in pharmaceutical preparations and so has no official indication. It is typically present in topical formulations as an emollient and occlusive agent .
Cornigel Eye is also used to associated treatment for these conditions: Eye lubrication, Skin protectionConstipation
How Cornigel Eye works
Lanolin is an emollient. Emollients soften the skin by forming an occlusive oil film on the stratum corneum layer of the epithelium, thus decreasing the transepidermal water loss .
Mineral oil sits on the surface of the skin and in spaces between cells and provides a hydrophobic barrier . This barrier prevents trans-epidermal water loss to trap water in the skin. Overall this leads to greater hydration, flexibility, and softness of the stratum corneum.
Toxicity
Studies have shown a positive association between atopic dermatitis and lanolin contact allergy . The prevalence of lanolin allergy is low (1.8%-2.5%) . Patch testing with lanolin is helpful in patients with dermatitis and suspected cosmetic allergy .
The acute dermal LD50 of lanolin oil was > 10 mL/kg for rabbits .
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