Corpea

Corpea Uses, Dosage, Side Effects, Food Interaction and all others data.

Corpea is an orally active, long-acting vasodilator, which belongs to the class of medications known as syndnones. Interestingly, it is being studied as being a preventive measure in cerebral infarction .

Corpea leads to smooth muscle relaxation in the coronary blood vessels, relieving symptoms of angina and increasing blood flow to the coronary arteries.

Trade Name Corpea
Generic Molsidomine
Molsidomine Other Names Molsidomina, Molsidomine, Molsidominum
Type
Formula C9H14N4O4
Weight Average: 242.235
Monoisotopic: 242.101504947
Groups Approved, Investigational
Therapeutic Class
Manufacturer
Available Country Spain
Last Updated: September 19, 2023 at 7:00 am
Corpea
Corpea

Uses

Corpea is a long-acting vasodilator used to treat angina pectoris, including in association with left heart failure and acute myocardial infarction.

The indications for use of molsidomine include ischemic heart disease, angina, chronic heart failure, and pulmonary hypertension .

Corpea is also used to associated treatment for these conditions: Angina Pectoris, Chronic Stable Angina Pectoris, Unstable Angina Pectoris

How Corpea works

Corpea, a cardiovascular drug, acts in a similar fashion to organic nitrates. The SIN-1A metabolite of molsidomine has a pharmacologically active group of nitric oxide, which increases levels of cyclic GMP, and decreases intracellular calcium ions in smooth muscle cells. This leads to relaxation of smooth muscle in the blood vessels, and inhibits platelet aggregation.

Volume of Distribution

98 L

Elimination Route

Peak plasma drug concentration (tmax) occurs from 1 to 2 hours after administration.

Clearance

renal excretion is the main route of elimination of the metabolites in humans (90% to 95%) About 2% of the ingested drug is excreted unchanged in the urine.

Innovators Monograph

You find simplified version here Corpea

*** Taking medicines without doctor's advice can cause long-term problems.
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