Cosyntropin Uses, Dosage, Side Effects and more

Trade Name Cosyntropin
Availability Prescription only
Generic Cosyntropin
Related Drugs prednisone, dexamethasone, triamcinolone, hydrocortisone, Decadron
Weight 0.25mg
Type Injectable powder for injection
Therapeutic Class
Manufacturer
Available Country United States
Last Updated: January 7, 2025 at 1:49 am

Cosyntropin Hypertension interaction

[Major] Adrenocorticotropic agents may cause hypernatremia, hypokalemia, fluid retention, and elevation in blood pressure.

Therapy with these agents, particularly if intended for longer than brief periods, should be administered cautiously in patients with preexisting fluid retention or conditions that may be aggravated by these effects.

Dietary sodium restriction and potassium supplementation may be advisable.

The manufacturers consider the use of adrenocorticotropic agents to be contraindicated in patients with congestive heart failure or uncontrolled hypertension.

Drug Interaction

Moderate: furosemide, furosemide, polyethylene glycol 3350, polyethylene glycol 3350Unknown: sulfamethoxazole / trimethoprim, sulfamethoxazole / trimethoprim, loratadine, loratadine, docusate, docusate, duloxetine, duloxetine, levofloxacin, levofloxacin, pregabalin, pregabalin, dextromethorphan / guaifenesin, dextromethorphan / guaifenesin, tapentadol, tapentadol

Disease Interaction

Major: (+) tuberculin test, adrenal insufficiency, electrolyte imbalance, fluid retention, GI perforation, hyperadrenocorticism, infections, ocular herpes simplex, osteoporosis, PUD, scleroderma, vaccinationModerate: cirrhosis, depression/psychoses, diabetes, elevated IOP, hypothyroidism, myasthenia gravis, myopathy, thromboembolism

Innovators Monograph


*** Taking medicines without doctor's advice can cause long-term problems.
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