Cromoglicic Acid
Cromoglicic Acid Uses, Dosage, Side Effects, Food Interaction and all others data.
A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Cromoglicate or cromolyn (USAN), a synthetic compound, inhibits antigen-induced bronchospasms and, hence, is used to treat asthma and allergic rhinitis. Cromoglicate is used as an ophthalmic solution to treat conjunctivitis and is taken orally to treat systemic mastocytosis and ulcerative colitis.
Trade Name | Cromoglicic Acid |
Generic | Cromoglicic acid |
Cromoglicic acid Other Names | Acide Cromoglicique, Acido Cromoglicico, Acidum Cromoglicicum, Cromoglicate, Cromoglicic acid, Cromoglycate, Cromoglycic acid, Cromolyn |
Type | |
Formula | C23H16O11 |
Weight | Average: 468.3665 Monoisotopic: 468.069261354 |
Groups | Approved |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Cromoglicic Acid is a medication used to treat asthma, allergic reactions of the eyes and nose, as well as other mast cell reactions.
For the management of patients with bronchial asthma. Also used in the treatment of vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis.
Cromoglicic Acid is also used to associated treatment for these conditions: Asthma, Conjunctivitis, Vernal, Exercise-Induced Bronchospasm, Food Allergy, Keratoconjunctivitis, Perennial Allergic Rhinitis (PAR), Seasonal Allergic Conjunctivitis, Seasonal Allergic Rhinitis, Urticaria Pigmentosa, Vernal Keratoconjunctivitis
How Cromoglicic Acid works
Cromoglicate inhibits degranulation of mast cells, subsequently preventing the release of histamine and slow-reacting substance of anaphylaxis (SRS-A), mediators of type I allergic reactions. Cromoglicate also may reduce the release of inflammatory leukotrienes. Cromoglicate may act by inhibiting calcium influx.
Toxicity
Symptoms of overdose include cough, nasal congestion, nausea, sneezing and wheezing.
Food Interaction
- Take before a meal. Take cromolyn sodium 30 minutes before meals.
Elimination Route
1%
Half Life
1.3 hours
Innovators Monograph
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