Crystaderm

Crystaderm Uses, Dosage, Side Effects, Food Interaction and all others data.

Crystaderm is an oxidising agent with antibacterial and antiviral activity. It is used as an antiseptic, disinfectant, and deodorant. It also has a mild haemostatic action. It exerts its antiseptic action partly by its ready release of oxygen when applied to tissues, but this effect is reduced in the presence of organic matter. The mechanical effect of effervescence may be more useful for wound cleansing than the antimicrobial action.

Crystaderm exhibits antimicrobial properties against most forms of microorganisms, including dormant forms with known high resistance profiles, such as bacterial spores and protozoal cysts. It acts as an oxidative biocide to generate free radical species to induce DNA, protein and membrane lipid damage via oxidation.

Crystaderm
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Crystaderm
Generic	Hydrogen peroxide
Hydrogen peroxide Other Names	Hydrogen peroxide
Type
Formula	H₂O₂
Weight	Average: 34.0147 Monoisotopic: 34.005479308
Groups	Approved, Vet approved
Therapeutic Class	Oxidising agent with antibacterial and antiviral properties
Manufacturer
Available Country	New Zealand
Last Updated:	September 19, 2023 at 7:00 am

Uses

Crystaderm is a mild antiseptic used on the skin to prevent infection of minor cuts, scrapes, and burns. It may also be used as a mouth rinse to help remove mucus or to relieve minor mouth irritation (e.g., due to canker/cold sores, gingivitis). This product works by releasing oxygen when it is applied to the affected area. The release of oxygen causes foaming, which helps to remove dead skin and clean the area. This product should not be used to treat deep wounds, animal bites, or serious burns.

Crystaderm is also used to associated treatment for these conditions: Ear infection bacterial, Seborrheic Keratosis (SK), Excess ear wax, Superficial skin infections

How Crystaderm works

The production of free hydroxyl radicals in the Fenton reaction is thought to be the basis of biocidal actions of hydrogen peroxide. Free radicals eventually lead to oxidative damage proteins and membrane lipids in vivo . The oxidizing radical as the ferryl radical induces DNA oxidation .

Dosage

Crystaderm dosage

Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor orpharmacist. Donot use in theeyesor apply over large areas ofskin.

If you are using this product on the skin, clean the affected area before use. Apply a small amount of product on the affected area, usually 1 to 3 times daily or as directed by your doctor. If you apply a bandage after using this product, let the area dry first.

If you are using this product as amouthrinse, mix with an equal amount of water before using. Swish in themouthover the affected area for at least 1 minute, then spit out. Do not swallow this product. Rinse up to 4 times daily or as directed by your dentist or doctor.

Use this product regularly in order to get the most benefit from it. To help you remember, use it at the same time(s) each day.

Tell your doctor if your condition does not improve in 7 days or if it worsens. If you think you may have a serious medical problem, seek immediate medical attention.

Side Effects

Irritating burns on the skin and mucous membranes (strong solutions); reversible hypertrophy of the papillae of the tongue with continued use as mouthwash; gas embolism, rupture of the colon, proctitis, ulcerative colitis and gangrene of the intestines have occurred following colonic lavage with hydrogen peroxide solution.

Toxicity

Oral LD50 in mouse is 2000 mg/kg, and dermal LD50 is 4060 mg/kg in rat and 2000 mg/kg pig. LC50 of hydrogen peroxide vapours in rat is 2000 mg/m at 4 hours .

Oral ingestion of high dose hydrogen peroxide may cause chest and stomach pain, loss of consciousness, motor disorders, microhemorrhages and moderate leucocytosis in humans. Inhalation of highly concentrated vapours causes extreme irritation of nose and throat .

Crystaderm has no known carcinogenic potential. It was shown to be mutagenic to bacteria (Salmonella typhimurium) and the fungi, Neurospora crassa and Aspergillis chevallieri, and induced DNA damage in Escheria coli . It also caused sister chromatid exchanges and chromosomal aberrations in mammalian cells in vitro .

Precaution

Before using hydrogen peroxide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Interaction

If you are using this product under your doctor's direction, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Food Interaction

No interactions found.

Volume of Distribution

Target organs affected by hydrogen peroxide include the lungs, intestine, thymus, liver, and kidney .

Elimination Route

It is reported that hydrogen peroxide is decomposed before absorption in the intestine. Solutions of hydrogen peroxide displays poor penetration when applied to tissue .