Curin Tablet 5 mg

Curin Tablet 5 mg Uses, Dosage, Side Effects, Food Interaction and all others data.

Trade Name Curin Tablet 5 mg
Generic Levocetirizine Dihydrochloride
Weight 5 mg
Type Tablet
Therapeutic Class Non-sedating antihistamines
Manufacturer Beximco Pharmaceuticals Ltd.
Available Country Bangladesh
Last Updated: October 19, 2023 at 6:27 am
Curin Tablet 5 mg
Curin Tablet 5 mg

Uses

Levocetirizine is indicated in the treatment of symptoms associated with allergic conditions such as- perennial allergic rhinitis seasonal allergic rhinitis chronic idiopathic urticaria

Dosage

Curin Tablet 5 mg dosage

Adult and children 12 years of age and older: The recommendeddose is 5 mg once daily.Children 6 to 11 years of age: The recommended dose is 2.5 mg (½ tablet or 1 teaspoon oral solution) once daily.Children 6 months to 5 years of age: The recommended dose is 1.25 mg (½ teaspoon oral solution) once daily.Pediatric use: The recommended dose for the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria in patients 6 months to 17 years of age is based on extrapolation of efficacy from adults 18 years of age and older.Geriatric use: In clinical studies, each approved indication did not include sufficient numbers of patients aged 65 years and older to determine whether they respond differently than younger patients.Hepatic impairment: No dosage adjustment is required in patients with solely hepatic impairment.Renal impairment: Mild renal impairment (creatinine clearance: 50-80 ml/min): a dose of 2.5 mg once daily is recommended. Moderate renal impairment (creatinine clearance: 30-50 ml/min): a dose of 2.5 mg once every other day is recommended. Severe renal impairment (creatinine clearance: 10-30 ml/min): a dose of 2.5 mg twice weekly (administered once every 3-4 days) is recommended. End-stage renal disease patients (creatinine clearance: <10 ml/min) and patients undergoing hemodialysis: should not receive Levocetirizine.

Side Effects

Generally, levocetirizine is well tolerated. However, a few side effects like headache, dry mouth, fatigue and skin rash have been reported rarely.

Precaution

Epileptic patients and patients at risk of convulsions. Renal impairment. Pregnancy and lactation.

Interaction

Levocetirizine is not known to have any interactions with other drugs.

Pregnancy & Breastfeeding use

Pregnancy Catagory B. There are no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, levocetirizine should be used during pregnancy only if clearly needed. Since levocetirizine is excreted in breast milk it is not recommended for use by nursing mothers.

Contraindication

Hypersensitivity to levocetirizine, cetirizine or its parent compound hydroxyzine. Patients with severe renal impairment (creatinine clearance: <10 ml/min) should not be administered levocetirizine.

Acute Overdose

No clinically relevant adverse events have been reported in case of overdose. However in the event of overdosage, symptomatic and supportive treatment is recommended.

Storage Condition

Store at a temperature not exceeding 30°C in a dry place. Protect from light.

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