D-40000 Capsule 40000 IU

D-40000 Capsule 40000 IU Uses, Dosage, Side Effects, Food Interaction and all others data.

Trade Name D-40000 Capsule 40000 IU
Generic Cholecalciferol [Vitamin D3]
Weight 40000 IU
Type Capsule
Therapeutic Class Vitamin in bone formation, Vitamin-D preparations
Manufacturer Ibn Sina Pharmaceuticals Ltd.
Available Country Bangladesh
Last Updated: October 19, 2023 at 6:27 am
D-40000 Capsule 40000 IU
D-40000 Capsule 40000 IU

Uses

Vitamin D3 deficiency can occur in people whose exposure to sunlight is limited and in those whose diet is deficient in vitamin D3. Vitamin D3 is essential for the effective calcium and phosphate absorption required for healthy bones and teeth,preventing rickets, osteomalacia and osteoporosis. Vitamin ... Read more

Dosage

D-40000 Capsule 40000 IU dosage

For capsule: Adults: Treatment of Vitamin D3 deficiency: 40000 IU once weekly for 7 weeks. Doses for maintenance therapy is 1400-2000 IU/day. To confirm the target level of 25 hydroxyvitamin D, measurement of it should be determined 3-4 months after initiating the maintenance therapy. Prevention of Vitamin D3 deficiency: 20000 IU every 4 weeks. Higher doses may be required in certain situations. Addition to specific therapy for osteoporosis: 20000 IU once a month. For capsule: Children (12-18 years): Treatment of Vitamin D3 deficiency: 20000 IU once every 2 weeks for 6 weeks. Prevention of Vitamin D3 deficiency: 20000 IU every 6 weeks. For film-coated tablet: 1000 IU (1-2 tablets) daily, or as directed by physician. Take the medicine with food or within 1 hour after a meal.For oroflash or chewable tablets: 1000 IU to 2000 IU daily, or as directed by physician. Take the medicine with food or within 1 hour after a meal. Place the tablet in mouth swallow after chewing.For Syrup:For patients with risk of Cholecalciferol deficiency: 0-1 yr: 400 IU/ day (2 ml) >1 Yr: 600 lU/ day (3 ml) For Cholecalciferol deficient patients: 0-1 yr: 2000 IU/ day (+50000 IU/week ) for 6 weeks 1 -18 yrs: 2000 IU/ day for 6 weeks. Injection: Prevention: Infants receiving Vitamin D enriched milk: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. every 6 months. Nursed infants or infants not receiving Vitamin D enriched milk or young children up to 5 years of age: 1 ampoule (1ml) i.e. 2,00000 I.U. every 6 months. Adolescents: 1 ampoule (1ml) i.e. 2,00000 I.U. every 6 months during winter. Pregnancy: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. from the 6th or 7th month of pregnancy. Elderly: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. every 3 months. Digestive disorders, concomitant treatment with antiepileptics & other particular condition not described above; 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. or 1 ampoule (1ml) i.e. 2,00000 I.U. every 3 or 6 months. Injection: Vitamin D deficiency: 1 ampoule (1ml) i.e. 2,00000 I.U. which can be repeated 1 to 6 months later. Or, as directed by the registered physician.

Side Effects

Symptoms rarely include anorexia, lassitude, nausea & vomiting, diarrhea, constipation, weight loss, polyuria, sweating, headache, thirst, vertigo, and raised concentrations of calcium and phosphate in plasma and urine.

Precaution

Plasma-calcium concentration should be monitored at intervals in patients receiving high doses of Vitamin D3, in renal impairment, and during pregnancy & lactation. People using Digoxin and Thiazide Diuretics should consult a health care practitioner before supplementing with Vitamin D3. People with liver or kidney disease, primary hyperthyroidism, lymphoma, tuberculosis and granulomatous disease should consult a health care practitioner before supplementing with Vitamin D3.

Interaction

Many drugs cause Vitamin D3 deficiencies because they interfere with the absorption and metabolism of Vitamin D3 and includes Magnesium containing Antacids, Digoxin, Thiazide Diuretics, Cholestyramine, Cholistipol, Phenytoin, Phenobarbital, Orlistat,and Mineral Oil. Also, Corticosteroids, such as Prednisolone increase the need for Vitamin D3.

Pregnancy & Breastfeeding use

Studies have shown safe use of doses up to 4000 IU during pregnancy. The recommended daily intake for pregnant women is 400 IU, however, in women who are considered to be Vitamin D3 deficient a higher dose may be required. During pregnancy women should follow the advice of their medical practitioner as their requirements may vary depending on the severity of their disease and their response to treatmentVitamin D3 and its metabolites are excreted in breast milk. Overdose in infants induced by nursing mothers has not been observed; however, when prescribing additional vitamin D3 to a breast-fed child the practitioner should consider the dose of any additional vitamin D3 given to the mother.

Contraindication

Vitamin D3 is contraindicated in all diseases associated with hypercalcaemia. It is also contraindicated in patients with known hypersensitivity to Vitamin D3 (or medicines of the same class) and any of the excipients. It is contraindicated if there is evidence of Vitamin D3 toxicity.

Special Warning

The safety & efficacy of Vitamin D3 in children under 12 years have not been established.

Acute Overdose

It can lead to hypervitaminosis D.

Storage Condition

Keep below 30º C temperature, protected from light & moisture. Keep out of the reach of children.

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*** Taking medicines without doctor's advice can cause long-term problems.
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