Daglutril Uses, Dosage, Side Effects and more
Daglutril is an orally active, mixed neutral endopeptidase/endothelin converting enzyme inhibitor under development for the treatment of essential hypertension and congestive heart failure.
| Attribute | Details |
|---|---|
| Trade Name | Daglutril |
| Generic | Daglutril |
| Daglutril Other Names | Daglutril |
| Type | |
| Formula | C31H38N2O6 |
| Weight | Average: 534.6432 Monoisotopic: 534.272986958 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in congestive heart failure and hypertension.
How Daglutril works
SLV306 increased plasma natriuretic peptides and big endothelin-1 levels in a dose-dependent manner, confirming neutral endopeptidase and endothelin-converting enzyme inhibition. The combined inhibition of neutral endopeptidase and endothelin-converting enzyme may be useful in heart failure by reducing right and left cardiac filling pressures
