Daglutril
Daglutril Uses, Dosage, Side Effects, Food Interaction and all others data.
Daglutril is an orally active, mixed neutral endopeptidase/endothelin converting enzyme inhibitor under development for the treatment of essential hypertension and congestive heart failure.
Trade Name | Daglutril |
Generic | Daglutril |
Daglutril Other Names | Daglutril |
Type | |
Formula | C31H38N2O6 |
Weight | Average: 534.6432 Monoisotopic: 534.272986958 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in congestive heart failure and hypertension.
How Daglutril works
SLV306 increased plasma natriuretic peptides and big endothelin-1 levels in a dose-dependent manner, confirming neutral endopeptidase and endothelin-converting enzyme inhibition. The combined inhibition of neutral endopeptidase and endothelin-converting enzyme may be useful in heart failure by reducing right and left cardiac filling pressures
Innovators Monograph
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