Dalfopristine

Dalfopristine Uses, Dosage, Side Effects, Food Interaction and all others data.

Dalfopristine is a combination of two antibiotics (Dalfopristine and quinupristin) used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium. It is not effective against Enterococcus faecalis infections. Dalfopristine inhibits the early phase of protein synthesis in the bacterial ribosome and quinupristin inhibits the late phase of protein synthesis.

Dalfopristine is a streptogramin antibiotic, derived from pristinamycin IIA.

Table Of contents

• Dalfopristine
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Dalfopristine
Generic	Dalfopristin
Dalfopristin Other Names	Dalfopristin, Dalfopristina, Dalfopristine, Dalfopristinum
Type
Formula	C34H50N4O9S
Weight	Average: 690.85 Monoisotopic: 690.32985038
Protein binding	Moderate
Groups	Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Dalfopristine is an antibiotic used with quinupristin to treat severe or life-threatening infections of vancomycin-resistant Enterococcus faecium (VREF), and skin infections caused by methicillin susceptible staphylococcus aureus or streptococcus pyogenes.

For the treatment of bacterial infections (usually in combination with quinupristin).

Dalfopristine is also used to associated treatment for these conditions: Bacterial Infections, Infections caused by penicillinase-producing staphylococci, Complicated Skin and subcutaneous tissue bacterial infection

How Dalfopristine works

The site of action of dalfopristin is the bacterial ribosome. Dalfopristine has been shown to inhibit the early phase of protein synthesis.

Food Interaction

No interactions found.

Half Life

The elimination half-life is approximately 0.70 hours.

Innovators Monograph

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