Dapiprazol

Dapiprazol Uses, Dosage, Side Effects, Food Interaction and all others data.

Dapiprazol (U.S. trade name Rev-Eyes) is an alpha blocker. It is found in ophthalmic solutions used to reverse mydriasis after an eye examination.

Dapiprazol is an alpha-adrenergic blocking agent. It produces miosis by blocking the alpha-adrenergic receptors on the dilator muscle of the iris. Dapiprazol produces no significant action on ciliary muscle contraction and thus, there are no changes in the depth of the anterior chamber of the thickness of the lens. It does not alter the IOP either in normal eyes or in eyes with elevated IOP. The rate of pupillary constriction may be slightly slower in clients with brown irises than in clients with blue or green irises.

Trade Name Dapiprazol
Generic Dapiprazole
Dapiprazole Other Names Dapiprazol, Dapiprazole, Dapiprazolum
Type
Formula C19H27N5
Weight Average: 325.4512
Monoisotopic: 325.226645889
Groups Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Dapiprazol
Dapiprazol

Uses

Used in the treatment of iatrogenically induced mydriasis produced by adrenergic (phenylephrine) or parasympatholytic (tropicamide) agents used in certain eye examinations.

Dapiprazol is also used to associated treatment for these conditions: Iatrogenically induced mydriasis

How Dapiprazol works

Dapiprazol acts through blocking the alpha1-adrenergic receptors in smooth muscle. It produces miosis through an effect on the dilator muscle of the iris and does not have any significant activity on ciliary muscle contraction and, therefore does not induce a significant change in the anterior chamber depth or the thickness of the lens.

Toxicity

Oral LD50 is 1189-2100 mg/kg in mice, rats and rabbits.

Food Interaction

No interactions found.

Elimination Route

Systemic absorption is negligible.

Innovators Monograph

You find simplified version here Dapiprazol

*** Taking medicines without doctor's advice can cause long-term problems.
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