DDP-200
DDP-200 Uses, Dosage, Side Effects, Food Interaction and all others data.
DDP200 is developed by Dynogen for the treatment of non-incontinent form of overactive bladder (OAB) with particular focus on both male and female patients with urinary frequency, urinary urgency and nocturia.
| Trade Name | DDP-200 |
| Generic | DDP-200 |
| Type | |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in urinary incontinence.
How DDP-200 works
DDP200 is an oral, fixed dose, combination of gabapentin and oxybutynin. Oxybutynin is prescribed to treat symptoms of lower urinary tract disorders such as overactive bladder (OAB), while gabapentin is prescribed for the management of postherpetic neuralgia and epilepsy. Dynogen’s combination of the two drugs has shown statistically significant synergy in Dynogen’s preclinical models of OAB, suggesting that a low dose combination of the two drugs will have improved efficacy over oxybutynin alone, without the side effects seen at higher doses. The combination of the two drugs has important characteristics: it affects both the afferent and efferent neurological pathways serving the bladder, and therefore may have benefits for both the sensory and motor aspects of OAB. Dynogen expects the synergy between the two compounds to increase the efficacy and tolerability profiles compared to market leading drugs for OAB.
Innovators Monograph
You find simplified version here DDP-200
