Debion

Debion Uses, Dosage, Side Effects, Food Interaction and all others data.

Vitamin B1 (Thiamine) forms thiamine pyrophosphate by combining with adenosine triphosphate; essential coenzyme in carbohydrate metabolism.

Vitamin B6 (Pyridoxine) is a water-soluble vitamin which functions in the metabolism of carbohydrates, proteins and fats. It is essential in Hb formation and GABA synthesis within the CNS. It also aids in the release of glycogen stored in the liver and muscles.

Vitamin B12 (cobalamin) is a water-soluble vitamin that has a key role in the normal functioning of the brain and nervous system, and the formation of red blood cells. It is one of eight B vitamins. It is involved in the metabolism of every cell of the human body, especially affecting DNA synthesis, fatty acid and amino acid metabolism.

Vitamin B1 (Thiamine), B6 (Pyridoxine) & B12 (Cyanocobalamin) play essential role as co-enzyme for the metabolism of nervous system. Thus this combination normalizes the nerve cell metabolism. This combination supports the regeneration of nerve fibers and myelin sheath by activation of the metabolism and the natural repair mechanism. The combination of these 3 vitamins shows better efficacy than that of the individual components. In addition, Vitamin B1, B6 & B12 promote body's own repair mechanism and work in pain management

Debion
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Debion
Generic	Vitamin B1, B6 + B12
Weight	100mg+200mg+200mcg, (100mg+100mg+1 mg) / 3ml
Type	Tablet, Im Injection
Therapeutic Class	Specific combined vitamin preparations
Manufacturer	Delta Pharma Limited
Available Country	Bangladesh
Last Updated:	September 19, 2023 at 7:00 am

Uses

Each tablet contains-

Thiamine Nitrate (Vitamin B1) 100 mg
Pyridoxine Nitrate (Vitamin B6) 200 mg
Cyanocobalamin (Vitamin B12) 200 mcg.

Each 3 ml ampoule contains-

Thiamine Hydrochloride (Vitamin B1) 100 mg
Pyridoxine Hydrochloride (Vitamin B6) 100 mg
Cyanocobalamin (Vitamin B12) 1000 mcg.

Vitamin B1, B6 & B12 is used for the treatment of B1, B6 and B12 deficiency syndrome. It is also used for the treatment of:

Diabetic neuropathy
Sciatica
Peripheral neuralgia
Facial neuralgia
Lumbago
Intercostal neuralgia
Myalgia
Spinal pain

Dosage

Debion dosage

Tablets may be administered in a dose of 1 to 3 tablets per day or as directed by the physician.

Ampoules are preferably injected intramuscularly (deep intragluteal). In severe cases 1 ampoule daily until the acute symptoms subside. For milder cases and follow up therapy 2 to 3 ampoules per week.

Side Effects

Generally well tolerated. However, a few allergic reactions may be seen.

Precaution

Cyanocobalamin should not be given before a diagnosis has been fully established because of the possibility of masking symptoms of subacute degeneration of the spinal cord. Cyanocobalamin is not a suitable form of Vitamin B12 for the treatment of optic neuropathies associated with raised plasma concentrations of cyanocobalamin.