Dezini
Dezini Uses, Dosage, Side Effects, Food Interaction and all others data.
Zinc is an essential trace mineral, which means that it must be obtained from the diet since the body cannot make enough. Next to iron, zinc is the most abundant trace mineral in the body. Stored primarily in muscle, zinc is also found in high concentrations in red and white blood cells, the retina of the eye, bones, skin, kidneys, liver, and pancreas. Some of the symptoms of zinc deficiency include loss of appetite, poor growth, weight loss, impaired taste or smell, poor wound healing, skin abnormalities (such as acne, atopic dermatitis and psoriasis), hair loss, night blindness, hypogonadism and delayed sexual maturation, white spots on the fingernails and feelings of depression.
| Trade Name | Dezini |
| Generic | Zinc Sulphate Monohydrate |
| Weight | 10mg/5ml |
| Type | Syrup |
| Therapeutic Class | Specific mineral preparations |
| Manufacturer | Zephyr Pharmatec (pvt) Ltd, |
| Available Country | Pakistan |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Zinc Sulphate is used for Recurrent Respiratory Tract Infections; Diarrhoea; Loss of appetite; Severe growth retardation; Deformed bone formation; Impaired immunological response; Acrodermatitis enteropathica; Parakeratatic skin lesions; Defective and delayed wound healing; Anaemia; Night blindness; Mental disturbances
Dosage
Dezini dosage
Syrup-
- Children under 10 kg: One teaspoonful 2 times daily.
- Children within 10 to 30 kg: Two teaspoonful 1-3 times daily.
- Adults and children over 30 kg body weight: Four teaspoonful 1-3 times daily.
Tablet-In the treatment of Diarrhoea Zinc should be given as soon as diarrhoea starts:
- For infants between 2 to 6 months of age: 10 mg Zinc once daily for 10-14 days.
- For children between 6 months to 5 years of age: 20 mg Zinc once daily for 10-14 days.
For other indications:
- The recommended dose for children: 2 to 2.5 mg/kg/day.
- Children under 10 kg: 10 mg Zinc 2 times daily.
- Children within 10 to 30 kg: 20 mg Zinc 1-3 times daily.
- Adults and children over 30 kg body weight: 40 mg Zinc 1-3 times daily.
Dispersible Tablet-
- Place the tablet in a teaspoon
- Add adequate amount of water
- Let the tablet dissolve completely
- Give the entire spoonful solution
Side Effects
In case of zinc mild side effects such as gastric ulcer, nausea, vomiting, metallic taste, headache, drowsiness have been observed.
Precaution
Concurrent administration of Zinc salt with penicillamine might diminish the effect of Penicillamine. The absorption of Zinc, although poor, may be decreased by various compounds including some foods. Chelation may occur with tetracyclines.
Interaction
Zinc may inhibit the absorption of concurrently administered tetracyclines, when both are being given an interval of at least 3 hours.
Pregnancy & Breastfeeding use
Pregnant women and nursing mothers should avoid zinc doses higher than RDA amounts.
Contraindication
It is contraindicated in patients with hypersensitivity to Zinc.
Acute Overdose
Zinc sulphate is corrosive in overdose. Symptoms are corrosion and inflammation of the mucous membrane of the mouth and stomach; ulceration of the stomach followed by perforation may occur. Gastric lavage and emesis should be avoided. Demulcents such as milk should be given. Chelating agents such as sodium edetate may be useful.
Storage Condition
Store in a cool place. The syrup should be protected from light.
Innovators Monograph
You find simplified version here Dezini
FAQ
What is Dezini used for?
Zinc sulfate is used medically as a dietary supplement. Specifically it is used to treat zinc deficiency and to prevent the condition in those at high risk. This includes use together with oral rehydration therapy for children who have diarrhea.
Is Dezini safe?
Dezini (Zinc sulphate monohydrate) is considered as a safe source of zinc for all animal species, regarding the maximum contents for total zinc in feedingstuffs set by the EU.
Is zinc sulphate monohydrate same as zinc?
Zinc sulfate and its hydrates are colourless solids.
Does Dezini stop Diarrhoea?
Dezini supplementation is a critical new intervention for treating diarrheal episodes in children. Recent studies suggest that administration of zinc along with new low osmolarity oral rehydration solutions / salts (ORS), can reduce the duration and severity of diarrheal episodes for up to three months.
How much Dezini should I take?
The recommended dietary allowance for elemental zinc is 11 mg daily for men and 8 mg for nonpregnant women.
When should I take Dezini?
Zinc supplements are most effective if they are taken at least 1 hour before or 2 hours after meals. However, if zinc supplements cause stomach upset, they may be taken with a meal.
Is zinc good for sperm?
Zinc is an essential mineral for sperm formation, and folate, the natural form of folic acid, depends on zinc to help form DNA in the sperm.
Which zinc is best for diarrhea?
Zinc is usually given as zinc sulphate, zinc acetate, or zinc gluconate, which are all water-soluble compounds. The World Health Organization (WHO) and the United Nations Children's Fund (UNICEF) recommend 10 mg to 20 mg of zinc per day for children with diarrhoea.
Is it safe to take Dezini during pregnancy?
Dezini has been assigned to pregnancy category C by the FDA. Safety for use in pregnancy has not been established. The risk of fetal harm if used during pregnancy is remote. A dietary intake of 11 mg of zinc per day (19 to 50 years of age) and 12 mg per day (14 to 18 years of age) is recommended during pregnancy.
What are the side effects of Dezini?
Side effects of Dezini:
- nausea
- vomiting
- gastric irritation
- elevation of serum alkaline phosphate, amylase, and lipase that may return to high normal within 1-2 years of therapy
- neurologic deterioration
Is it safe to take Dezini during breastfeeding?
Dezini is present in breast milk, use caution if breastfeeding.
