Diaethylnicotinamid
Diaethylnicotinamid Uses, Dosage, Side Effects, Food Interaction and all others data.
Diaethylnicotinamid was formerly used as a respiratory stimulant but its use for this indication is no longer recommended as the effective doses are close to those causing toxic effects (especially convulsions).
Trade Name | Diaethylnicotinamid |
Generic | Nikethamide |
Nikethamide Other Names | Nikethamide |
Type | |
Formula | C10H14N2O |
Weight | Average: 178.235 Monoisotopic: 178.110613079 |
Groups | Experimental |
Therapeutic Class | Respiratory stimulants: analeptics |
Manufacturer | |
Available Country | Russia |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Central respiratory depression, Energy malnutrition, Tranquilizer overdoses
Diaethylnicotinamid is also used to associated treatment for these conditions: Respiratory stimulation
Dosage
Diaethylnicotinamid dosage
1500 mg as single dose
Side Effects
Dyspnoea, respiratory problems; muscular, GI, CNS and CV effects. Convulsions.
Precaution
Less severe degrees of hypertension or impaired cardiac reserve; liver dysfunction.
Interaction
Additive pressor effects with sympathomimetics or MAOIs. Increased risk of cardiac arrythmias with some anaesthetics (halothane, enflurane, isoflurane). May mask the effects of neuromuscular blockers. Increased risk of convulsions with bupropion.
Pregnancy & Breastfeeding use
Pregnancy category- Not classified
Contraindication
Porphyria, epilepsy or other convulsive disorders, cerebral oedema, cerebrovascular accident, head injury, acute severe asthma, physical obstruction of the airway, severe hypertension, ischaemic heart disease, hyperthyroidism, phaeochromocytoma.
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