Dibasic Aluminium Stearate
Dibasic Aluminium Stearate Uses, Dosage, Side Effects, Food Interaction and all others data.
Dibasic Aluminium Stearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2. Also known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging of pharmaceuticals and in the preparation of colors for cosmetics. While considered safe for use, extensive usage may result in aluminum accumulation.
| Trade Name | Dibasic Aluminium Stearate |
| Generic | Aluminium monostearate |
| Aluminium monostearate Other Names | Aluminum monostearate, Aluminum stearate 300, Dibasic aluminium stearate, Dibasic aluminum stearate, Dihydroxyaluminum stearate |
| Type | |
| Formula | C18H37AlO4 |
| Weight | Average: 344.472 Monoisotopic: 344.2507232 |
| Groups | Experimental |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
How Dibasic Aluminium Stearate works
Antacids perform a neutralization reaction, ie. they buffer gastric acid, raising the pH to reduce acidity in the stomach. When gastric hydrochloric acid reaches the nerves in the gasitrointestinal mucosa, they signal pain to the central nervous system. This happens when these nerves are exposed, as in peptic ulcers. The gastric acid may also reach ulcers in the esophagus or the duodenum. Other mechanisms may contribute, such as the effect of aluminum ions inhibiting smooth muscle cell contraction and delaying gastric emptying. Aluminum is known to bind troponin C (a muscle protein) and to interfere with voltage-dependent calcium transport. Aluminum also binds to and inhibits the activity of mitochondrial voltage gated channels (VDAC).
Innovators Monograph
You find simplified version here Dibasic Aluminium Stearate
