Didronel

Didronel Uses, Dosage, Side Effects, Food Interaction and all others data.

Trade Name	Didronel
Availability	Discontinued
Generic	Etidronate
Related Drugs	Prolia, prednisone, hydrochlorothiazide, dexamethasone, alendronate, calcitonin, Fosamax, Decadron, denosumab, Reclast
Type
Therapeutic Class
Manufacturer
Available Country	United States,
Last Updated:	September 19, 2023 at 7:00 am

Food Interaction

[Moderate] ADJUST DOSING INTERVAL: Food, especially calcium-containing food such as dairy products, significantly decreases the bioavailability of oral etidronate.

MANAGEMENT: Oral etidronate should be administered on an empty stomach and no other food or drink should be taken within least 2 hours of administration.

Didronel multivitamins interaction

[Moderate] ADJUST DOSING INTERVAL: Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to interfere with the gastrointestinal absorption of oral bisphosphonates.

For example, the bioavailability of tiludronate has been shown to decrease 80% during simultaneous administration with calcium, and 60% when aluminum- or magnesium-containing antacids were administered one hour before tiludronate.

Antacids or other oral medications containing aluminum, calcium, magnesium and other polyvalent cations should be administered at least 2 hours before or 2 hours after the bisphosphonate dose.