Diethylcarbamazine Citrate

Diethylcarbamazine Citrate Uses, Dosage, Side Effects, Food Interaction and all others data.

Trade Name Diethylcarbamazine Citrate
Generic Diethylcarbamazine Citrate
Type
Therapeutic Class Other Anti-protozoals
Manufacturer
Available Country Bangladesh
Last Updated: September 24, 2024 at 5:38 am
Diethylcarbamazine Citrate
Diethylcarbamazine Citrate

Uses

Diethylcarbamazine is indicated for Filariasis, Lymphatic filariasis, Pulmonary eosinophilia, Loiasis, Toxocariasis.

Dosage

Diethylcarbamazine Citrate dosage

Inital: 1 mg/kg/day, may increase to 6 mg/kg/day over 3 days, then maintain for 3 wk. Prophylaxis of loiasis 300 mg/wk.

Side Effects

Fever, headache, vomiting, dizziness, drowsiness, nausea, chills.Potentially Fatal: Severe hypersensitivity reactions may occur especially in the treatment of onchocerciasis where rare Mazzotti reaction characterised by rash, itching, headache, muscle and joint pains, tachycardia, postural hypotension may start within 2 hr of drug administration. Encephalitis and retinal haemorrhage.

Precaution

Patients with poor health.Lactation: not known if excreted in breast milk

Interaction

There are no known drug interactions and none well documented.

Pregnancy & Breastfeeding use

Pregnancy Category- X. Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Contraindication

Pregnancy, hypersensitivity; lactation; infants, elderly or debilitated patients; impaired renal function; cardiac disease.

Innovators Monograph

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