Dimetapp Allergy

Dimetapp Allergy Uses, Dosage, Side Effects, Food Interaction and all others data.

Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.

Dimetapp Allergy is an antihistaminergic medication of the propylamine class. It is a first-generation antihistamine. In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Dimetapp Allergy is a histamine H1 antagonist (or more correctly, an inverse histamine agonist) of the alkylamine class. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.

Dimetapp Allergy
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Dimetapp Allergy
Availability	Rx and/or OTC
Generic	Brompheniramine
Brompheniramine Other Names	Bromfeniramina, Brompheniramin, Bromphéniramine, Brompheniramine, Brompheniraminum
Related Drugs	prednisone, cetirizine, loratadine, fluticasone nasal, promethazine, diphenhydramine, triamcinolone, Benadryl, Zyrtec, chlorpheniramine
Weight	2mg/5ml
Type	Oral liquid
Formula	C₁₆H₁₉BrN₂
Weight	Average: 319.239 Monoisotopic: 318.073161265
Groups	Approved
Therapeutic Class
Manufacturer
Available Country	United States
Last Updated:	September 19, 2023 at 7:00 am

Uses

Dimetapp Allergy is a histamine H1 antagonist used to treat coughs, upper respiratory symptoms, and nasal congestion associated with allergies and the common cold.

For the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing.

Dimetapp Allergy is also used to associated treatment for these conditions: Acute nasopharyngitis, Allergic Rhinitis (AR), Allergies, Common Cold, Cough, Cough caused by Common Cold, Coughing caused by Bronchitis, Fever, Flu caused by Influenza, Headache, Pollen Allergy, Rhinorrhoea, Airway secretion clearance therapy

How Dimetapp Allergy works

Dimetapp Allergy is an antagonist of the H1 histamine receptors with moderate antimuscarinic actions, as with other common antihistamines such as diphenhydramine. Due to its anticholindergic effects, brompheniramine may cause drowsiness, sedation, dry mouth, dry throat, blurred vision, and increased heart rate.

Toxicity

Oral, rat: LD₅₀ = 318 mg/kg. Signs of overdose include fast or irregular heartbeat, mental or mood changes, tightness in the chest, and unusual tiredness or weakness.

Food Interaction

Avoid alcohol.
Take with food.

[Moderate] GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents.

Use in combination may result in additive central nervous system depression and
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol.

Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.