Diphemanil Cation
Diphemanil Cation Uses, Dosage, Side Effects, Food Interaction and all others data.
Diphemanil Cation Methylsulfate is a quaternary ammonium anticholinergic. It binds muscarinic acetycholine receptors and thereby decreases secretory excretion of stomach acids as well as saliva and sweat.
| Trade Name | Diphemanil Cation |
| Generic | Diphemanil |
| Diphemanil Other Names | Diphemanil cation, Diphemanil ion |
| Type | |
| Formula | C20H24N |
| Weight | Average: 278.418 Monoisotopic: 278.190326197 |
| Groups | Approved, Vet approved, Withdrawn |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Used in the treatment of peptic ulcer, gastric hyperacidity, and hypermotility in gastritis and pylorospasm, and in the treatment of hyperhidrosis (excessive perspiration).
How Diphemanil Cation works
Diphemanil Cation Methylsulfate exerts its action by primarily binding the muscarinic M3 receptor. M3 receptors are located in the smooth muscles of the blood vessels, as well as in the lungs. This means they cause vasodilation and bronchoconstriction. They are also in the smooth muscles of the gastrointestinal tract (GIT), which help in increasing intestinal motility and dilating sphincters. The M3 receptors are also located in many glands which help to stimulate secretion in salivary glands and other glands of the body.
Elimination Route
Poorly absorbed from the gastrointestinal tract with an absolute bioavailability of 15 to 25%.
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