Distigmine Uses, Dosage, Side Effects and more
Distigmine is a parasympathomimetic agent with a longer duration of action and enhanced drug accumulation compared to Pyridostigmine and Neostigmine. It is an anticholinergic drug and long-acting reversible carbamate cholinesterase inhibitor that binds directly and competitively to the agonist binding sites of muscurinic receptors. Distigmine is available in several countries as a treatment of underactive detrusor and voiding dysfunction in the urinary tract where the active ingredient is distigmine bromide. It improves detrusor function thereby restoring normal voiding patterns in patients suffering from detrusor underactivity .
| Trade Name | Distigmine |
| Generic | Distigmine |
| Type | |
| Formula | C22H32N4O4 |
| Weight | Average: 416.521 Monoisotopic: 416.241258367 |
| Groups | Experimental |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Distigmine is a cholinesterase inhibitor indicated in the treatment of neurogenic bladder dysfunction or myasthenia gravis.
Distigmine is also used to associated treatment for these conditions: Myasthenia Gravis, Neurogenic Voiding Disorders
