Distigmine

Distigmine Uses, Dosage, Side Effects, Food Interaction and all others data.

Distigmine is a parasympathomimetic agent with a longer duration of action and enhanced drug accumulation compared to Pyridostigmine and Neostigmine. It is an anticholinergic drug and long-acting reversible carbamate cholinesterase inhibitor that binds directly and competitively to the agonist binding sites of muscurinic receptors. Distigmine is available in several countries as a treatment of underactive detrusor and voiding dysfunction in the urinary tract where the active ingredient is distigmine bromide. It improves detrusor function thereby restoring normal voiding patterns in patients suffering from detrusor underactivity .

Table Of contents

• Distigmine
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Distigmine
Generic	Distigmine
Type
Formula	C22H32N4O4
Weight	Average: 416.521 Monoisotopic: 416.241258367
Groups	Experimental
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Distigmine is a cholinesterase inhibitor indicated in the treatment of neurogenic bladder dysfunction or myasthenia gravis.

Distigmine is also used to associated treatment for these conditions: Myasthenia Gravis, Neurogenic Voiding Disorders

Innovators Monograph

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