DL-Pantothenol
DL-Pantothenol Uses, Dosage, Side Effects, Food Interaction and all others data.
DL-Pantothenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. DL-Pantothenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol). While pantothenic acid is optically active, only the dextrorotatory form (Dexpanthenol) is biologically active.
Dexpanthenol, the active form of panthenol, is enzymatically cleaved to form pantothenic acid (Vitamin B5), which is an essential component of Coenzyme A that acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the epithelium .
Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products, such as ointments and lotions for treatment of dermatological conditions to relieve itching or promote healing. Dermatological effects of the topical use of dexpanthenol include increased fibroblast proliferation and accelerated re-epithelialization in wound healing. Furthermore, it acts as a topical protectant, moisturizer, and has demonstrated anti-inflammatory properties .
| Trade Name | DL-Pantothenol |
| Generic | Panthenol |
| Panthenol Other Names | DL-panthenol, DL-Pantothenol, Pantenol, Panthenol, Panthenolum |
| Type | |
| Formula | C9H19NO4 |
| Weight | Average: 205.254 Monoisotopic: 205.131408096 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
DL-Pantothenol is an ingredient used in skin, hair care, and nutritional products but is not an approved medication.
DL-Pantothenol (containing a racemic mixture of dexpanthenol and levopanthenol) is not currently available in any FDA-approved products and therefore does not have an indication.
Please see Dexpanthenol for FDA-approved uses of the dextrorotatory form of DL-Pantothenol.
DL-Pantothenol is also used to associated treatment for these conditions: Dry Skin, Paralytic Ileus
How DL-Pantothenol works
DL-Pantothenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Dexpanthenol, the active form of panthenol, is enzymatically cleaved to form pantothenic acid (Vitamin B5), which is an essential component of Coenzyme A that acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the epithelium .
Dermatological effects of the topical use of dexpanthenol include increased fibroblast proliferation and accelerated re-epithelialization in wound healing. Furthermore, it acts as a topical protectant, moisturizer, and has demonstrated anti-inflammatory properties .
Food Interaction
No interactions found.Innovators Monograph
You find simplified version here DL-Pantothenol
