DNase I

DNase I Uses, Dosage, Side Effects, Food Interaction and all others data.

DNase I (DNase I) is a human enzyme responsible for the digestion of extracellular DNA7. It is normally found in saliva, urine, pancreatic secretions, and blood. Because of the hypothesis that increased concentrations of high-molecular-weight DNA is a factor for airway obstruction, abnormal viscoelastic properties of the sputum, and recurrent exacerbations of respiratory symptoms requiring parenteral antibiotics, aerosolized human DNase I has been administered to patients with cystic fibrosis. Currently, DNase I is being investigated against respiratory failure in COVID-19 in the clinical trial NCT04541979 (Aerosoliserat DNase for Treatment of Respiratory Failure in Severe COVID-19).

Trade Name DNase I
Generic Deoxyribonuclease I
Deoxyribonuclease I Other Names DNase I
Type
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
DNase I
DNase I

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