E-2012 Uses, Dosage, Side Effects and more
E-2012 is a gamma secretase modulator that is being evaluated as a potential new treatment for Alzheimer's disease.
| Trade Name | E-2012 |
| Generic | E-2012 |
| Type | |
| Formula | C25H26FN3O2 |
| Weight | Average: 419.5 Monoisotopic: 419.200905252 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in alzheimer's disease.
How E-2012 works
Gamma secretase plays a role in the production of beta-amyloid, a major component of plaque in the brain, which is thought to be a cause of Alzheimer's disease. E2012 is a new chemical entity discovered by Eisai and, in preclinical (laboratory) research, has shown some potential to reduce the production of beta-amyloid by modulating the function of gamma secretase.
