Ecabetum

Ecabetum Uses, Dosage, Side Effects, Food Interaction and all others data.

Ecabetum is a prescription eye drop for the treatment of dry eye syndrome. Ecabetum represents a new class of molecules that increases the quantity and quality of mucin produced by conjunctival goblet cells and corneal epithelia. Mucin is a glycoprotein component of tear film that lubricates while retarding moisture loss from tear evaporation. Ecabetum is currently marketed in Japan as an oral agent for treatment of gastric ulcers and gastritis.

Trade Name Ecabetum
Generic Ecabet
Ecabet Other Names Ecabet, Ecabetum
Type
Formula C20H28O5S
Weight Average: 380.498
Monoisotopic: 380.165744696
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Ecabetum
Ecabetum

Uses

For the treatment of reflux oesophagitis and peptic ulcer disease.

How Ecabetum works

Ecabetum reduces the survival of H. pylori in the stomach and inhibits pepsin activity in the gastric juice of experimental animals. Here we have investigated the effects of ecabet on some of the factors involved in the dynamics of the mucosal barrier, i.e. pepsins and mucins. Pepsin, acid and Helicobacter pylori are major factors in the pathophysiology of peptic ulcer disease and reflux oesophagitis. Ecabetum also acts as an inhibitor of H. pylori NADPH oxidase as well as urease. Inhibition of these enzymes prevents bacterial adhesion to gastric mucosa.

Innovators Monograph

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*** Taking medicines without doctor's advice can cause long-term problems.
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