Ensifentrine
Ensifentrine Uses, Dosage, Side Effects, Food Interaction and all others data.
Ensifentrine is under investigation in clinical trial NCT04535986 (A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD).
Trade Name | Ensifentrine |
Generic | Ensifentrine |
Ensifentrine Other Names | Ensifentrine |
Type | |
Formula | C26H31N5O4 |
Weight | Average: 477.565 Monoisotopic: 477.237604498 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
How Ensifentrine works
Ensifentrine is a dual inhibitor of phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4); it is also an activator of the cystic fibrosis transmembrane conductance regulator (CFTR). This drug has bronchodilatory and anti-inflammatory properties due to the dual inhibition; it also has mucous viscosity reduction and improved mucociliary clearance effects due to the CFTR activation. Ensifentrine is currently being investigated against COPD, cystic fibrosis, asthma, other respiratory diseases, and COVID-19.
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