Epalridase
Epalridase Uses, Dosage, Side Effects, Food Interaction and all others data.
Epalridase is aldose reductase inhibitor. The aldose reductase inhibitors have a distinct mechanism of action, affecting the underlying disease process in diabetic neuropathy, although the extent of the polyol pathway involvement is yet to be determined. Epalridase reduces sorbitol accumulation in the sciatic nerve, erythrocytes. Epalridase may improve motor and sensory nerve conduction velocity and subjective neuropathy symptoms.
Trade Name | Epalridase |
Generic | Epalrestat |
Epalrestat Other Names | Epalrestat |
Type | Tablet |
Formula | C15H13NO3S2 |
Weight | Average: 319.39 Monoisotopic: 319.033685631 |
Groups | Investigational |
Therapeutic Class | Aldose reductase inhibitor |
Manufacturer | East West Pharma |
Available Country | India |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Diabetic neuropathy
Dosage
Epalridase dosage
In general, for adults, take 1 tablet (50 mg of the active ingredient) at a time, three times daily, before meal. The dosage may be adjusted according to the age or symptoms.
Side Effects
The most commonly reported adverse reactions include abdominal pain, nausea, rash, itch, erythema and blister.
Precaution
Urine may turn yellowish brown or reddish after taking the medicine, because the yellowish brown or reddish color is attributed to components of this medicine.
Interaction
There are no known drug interactions and none well documented.
Pregnancy & Breastfeeding use
Pregnancy Category- Not Classified. FDA has not yet classified the drug into a specified pregnancy category
Contraindication
Hypersensitivity. Pregnant or breastfeeding.
Innovators Monograph
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