Ethylene-diamine

Ethylene-diamine Uses, Dosage, Side Effects, Food Interaction and all others data.

Ethylene-diamine is an organic compound that is used as a building block for the production of many other chemical products. It is also used as an excipient in many pharmacological preparations such as creams. Notably, ethylenediamine is a contact sensitizer capable of producing local and generalized reactions . Sensitivity to ethylenediamine may be identified with a clinical patch test.

Trade Name Ethylene-diamine
Generic Ethylenediamine
Ethylenediamine Other Names 1,2-diaminoethane, Aethaldiamin, edamine, ethane-1,2-diamine, Ethyleendiamine, Ethylendiamine, Ethylene-diamine, Ethylenediamine
Type
Formula C2H8N2
Weight Average: 60.0983
Monoisotopic: 60.068748266
Groups Approved, Experimental
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Ethylene-diamine
Ethylene-diamine

Uses

Ethylene-diamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.

Volume of Distribution

Vd = 0.133 l/kg

Elimination Route

After oral administration its bioavailability is about 0.34, due to a substantial first-pass effect.

Half Life

Ethylene-diamine has a short half life of ~0.55 hours .

Elimination Route

Renal excretion of the unchanged substance amounts to only about 18% after intravenous and 3% after oral administration.

Innovators Monograph

You find simplified version here Ethylene-diamine

*** Taking medicines without doctor's advice can cause long-term problems.
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