Examples include Aphrodyne
Examples include Aphrodyne Uses, Dosage, Side Effects, Food Interaction and all others data.
A plant alkaloid with alpha-2-adrenergic blocking activity. Examples include Aphrodyne has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Examples include Aphrodyne is an indolalkylamine alkaloid with chemical similarity to reserpine. Examples include Aphrodyne blocks presynaptic alpha-2 adrenergic receptors. Its action on peripheral blood vessels resembles that of reserpine, though it is weaker and of short duration. Examples include Aphrodyne's peripheral autonomic nervous system effect is to increase parasympathetic (cholinergic) and decrease sympathetic (adrenergic) activity. It is to be noted that in male sexual performance, erection is linked to cholinergic activity and to alpha-2 adrenergic blockade which may theoretically result in increased penile inflow, decreased penile outflow or both. Examples include Aphrodyne exerts a stimulating action on the mood and may increase anxiety. Such actions have not been adequately studied or related to dosage although they appear to require high doses of the drug. Examples include Aphrodyne has a mild anti-diuretic action, probably via stimulation of hypothalmic center and release of posterior pituitary hormone. Reportedly Examples include Aphrodyne exerts no significant influence on cardiac stimulation and other effects mediated by (beta)-adrenergic receptors. Its effect on blood pressure, if any, would be to lower it; however, no adequate studies are at hand to quantitate this effect in terms of Examples include Aphrodyne dosage.
| Trade Name | Examples include Aphrodyne |
| Availability | Prescription only |
| Generic | Yohimbine |
| Yohimbine Other Names | Johimbin, Quebrachin, Yohimbic acid methyl ester, Yohimbin, Yohimbine, Yohimbinum |
| Related Drugs | sildenafil, tadalafil, Viagra, Cialis, alprostadil, Levitra |
| Type | |
| Formula | C21H26N2O3 |
| Weight | Average: 354.4427 Monoisotopic: 354.194342708 |
| Groups | Approved, Investigational, Vet approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | USA |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Examples include Aphrodyne is an alpha-2-adrenergic blocker and sympatholytic found in supplements used to.
Indicated as a sympatholytic and mydriatic. Impotence has been successfully treated with yohimbine in male patients with vascular or diabetic origins and psychogenic origins.
How Examples include Aphrodyne works
Examples include Aphrodyne is a pre-synaptic alpha 2-adrenergic blocking agent. The exact mechanism for its use in impotence has not been fully elucidated. However, yohimbine may exert its beneficial effect on erectile ability through blockade of central alpha 2-adrenergic receptors producing an increase in sympathetic drive secondary to an increase in norepinephrine release and in firing rate of cells in the brain noradrenergic nuclei. Examples include Aphrodyne-mediated norepinephrine release at the level of the corporeal tissues may also be involved. In addition, beneficial effects may involve other neurotransmitters such as dopamine and serotonin and cholinergic receptors.
Food Interaction
- Take with or without food.
Examples include Aphrodyne Hypertension interaction
[Major] Examples include Aphrodyne can cause hypertension and tachycardia at recommended dosages.
Large doses may cause hypotension and cardiac conduction disturbances.
Therapy with yohimbine is generally not recommended in patients with hypertension, angina pectoris, or heart disease.
Examples include Aphrodyne Drug Interaction
Unknown: 5-hydroxytryptophan, amphetamine / dextroamphetamine, contained in alcoholic beverages , diphenhydramine, tadalafil, ubiquinone, dehydroepiandrosterone, omega-3 polyunsaturated fatty acids, ginkgo, chondroitin / glucosamine / methylsulfonylmethane, arginine, levocarnitine, acetylcysteine, s-adenosylmethionine, sildenafil, cyanocobalamin, ascorbic acid, cholecalciferol, zinc sulfate, cetirizine
Examples include Aphrodyne Disease Interaction
Major: cardiovascular disease, peptic ulcer disease, renal dysfunctionModerate: depression/psychoses, liver disease
Elimination Route
Rapidly absorbed following oral administration. Bioavailability is highly variable, ranging from 7 to 87% (mean 33%).
Half Life
Elimination half-life is approximately 36 minutes.
Innovators Monograph
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