Ezego L Orange Lemon Flavour Sugar Free
Ezego L Orange Lemon Flavour Sugar Free Uses, Dosage, Side Effects, Food Interaction and all others data.
In the colon it is broken down to short chain organic acids and increases osmotic pressure in the colon, thereby causing an increase in the stool water content and stool volume.
Lactitol helps to facilitate bowel movements by drawing water into the gastrointestinal tract. The oral administration of lactitol may reduce the absorption of concomitant medications - other oral medications should be administered at least 2 hours before or 2 hours after lactitol.
Trade Name | Ezego L Orange Lemon Flavour Sugar Free |
Generic | Lactitol + Ispaghula |
Weight | 10gm |
Type | Powder |
Therapeutic Class | |
Manufacturer | Syndicate Life Sciences Pvt Ltd |
Available Country | India |
Last Updated: | September 19, 2023 at 7:00 am |
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Uses
Constipation, Hepatic encephalopathy
Ezego L Orange Lemon Flavour Sugar Free is also used to associated treatment for these conditions: Constipation, Hepatic Encephalopathy (HE), Occasional Constipation, Chronic idiopathic constipation (CIC)
How Ezego L Orange Lemon Flavour Sugar Free works
Lactitol is an osmotic laxative - it exerts its pharmacologic effect by creating a hyperosmotic environment within the small intestine. The osmotic effect generated by lactitol draws water into the small intestine, which loosens stools and ultimately facilitates bowel movements.
Dosage
Ezego L Orange Lemon Flavour Sugar Free dosage
2 teaspoonfuls (20 gm) once or twice daily with plenty of water
Side Effects
Abdominal distension, flatulance and abdominal cramp.
Toxicity
The LD50 is 23 g/kg in mice and >30 g/kg in rats.
Experience with acute overdosage is limited, but is likely to involve significant gastrointestinal upset and diarrhea consistent with the pharmacologic profile of lactitol. Overdosage should be managed with symptomatic and supportive measures, where necessary.
Precaution
Lactose intolerance.
Volume of Distribution
Data regarding the volume of distribution of lactitol are unavailable.
Elimination Route
In healthy subjects under fed conditions, oral administration of 20 grams of lactitol resulted in a mean Tmax of 3.6 ± 1.2 hours, Cmax of 776 ± 253 ng/mL, and a mean AUC of 6,019 ± 1,771 ng*hr/mL.
Half Life
The average half-life of orally administered lactitol is 2.4 hours.
Clearance
Data regarding the clearance of lactitol are unavailable.
Elimination Route
Lactitol is not absorbed in the gastrointestinal tract to any significant extent. The vast majority of an ingested dose is likely degraded into organic acids in the colon and eliminated in the feces.
Pregnancy & Breastfeeding use
Pregnancy Category - Not Classified. FDA has not yet classified the drug into a specified pregnancy category.
Contraindication
Patients with known hypersensitivity to any of the active substance. Gastro-intestinal obstruction. Galactosaemia.
Innovators Monograph
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